POM121 and AGR2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		POM121	AGR2
Gene Name		POM121 transmembrane nucleoporin	anterior gradient 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Membrane Nuclear Membrane	Extracellular Region Mitochondrion Endoplasmic Reticulum
	Molecular Function		Dystroglycan Binding Protein Binding
	Biological Process	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport	Lung Goblet Cell Differentiation Mucus Secretion
Pathways		Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS		Subcutaneous adipose tissue ( 22589738)	Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin) ( 23648065) Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Protein-Protein Interactions		21 interactors: AGR2 AP2B1 APC ATXN1 BRCA1 CEP55 CEP76 CLDN3 COL4A3BP FXR2 GFAP GOLGA2 GYG1 HOMER3 LPXN NFKBIA PAXIP1 RBPMS TEX11 TRIM23 TRIP6	15 interactors: APP BRD7 CATSPER1 CCDC90B CRMP1 DAG1 FABP2 KRT31 LYPD3 MED31 MLH1 NUP62CL POM121 UBQLN1 UBQLN4
Entrez ID		9883	10551
HPRD ID		11448	05896
Ensembl ID		ENSG00000196313	ENSG00000106541
Uniprot IDs		Q96HA1	O95994 Q4JM46
PDB IDs			2LNS 2LNT
Enriched GO Terms of Interacting Partners?		Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Negative Regulation Of Signal Transduction Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Signaling Regulation Of Microtubule-based Process Regulation Of Protein Import Into Nucleus Positive Regulation Of Histone Methylation Mitotic Cytokinesis Regulation Of NF-kappaB Import Into Nucleus Regulation Of Signaling Regulation Of Protein Localization To Nucleus Regulation Of Centrosome Duplication Regulation Of Chromosome Organization Regulation Of Histone Acetylation Cell Cycle Regulation Of Nucleocytoplasmic Transport Regulation Of Centrosome Cycle Signaling Regulation Of Histone Methylation Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Schwann Cell Proliferation Cell Communication DNA Recombination Cellular Response To Stress Regulation Of Intracellular Protein Transport Regulation Of Signal Transduction Cell Cycle Process Positive Regulation Of Histone Modification Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Mucus Secretion Positive Regulation Of Histone H3-K9 Acetylation ER To Golgi Ceramide Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Signal Transduction Response To Abiotic Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Chromosome Organization Lung Goblet Cell Differentiation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Transcription Factor Import Into Nucleus Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Import Into Nucleus
Tagcloud ?		antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis	aacr acting adenocarcinomas autonomous besides coordinated disulfide drives exerting fibroblast fibroblasts folding gastric hypoxic incorporated isomerase microenvironment neoplastic organs paracrine participates physiologically res residing signet srcc stromal surrounding turn
Tagcloud (Difference) ?		antagonize brd1 brings childhood chimeric comprise dach1 encoding fluorescence frame fusion fusions hipk1 hybridization identification implicated least leukemia lymphoblastic master occur partner pax5 precursor rearrangements regulator situ transduction tumorigenesis	aacr acting adenocarcinomas autonomous besides coordinated disulfide drives exerting fibroblast fibroblasts folding gastric hypoxic incorporated isomerase microenvironment neoplastic organs paracrine participates physiologically res residing signet srcc stromal surrounding turn
Tagcloud (Intersection) ?