FCHSD2 and VCPIP1

Number of citations of the paper that reports this interaction (PMID 18654987)
7

Data Source:
BioGRID (two hybrid)

		FCHSD2	VCPIP1
Gene Name		FCH and double SH3 domains 2	valosin containing protein (p97)/p47 complex interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Endoplasmic Reticulum Golgi Stack
	Molecular Function	Protein Binding	Ubiquitin-specific Protease Activity
	Biological Process		Proteolysis Mitotic Nuclear Division Endoplasmic Reticulum Membrane Fusion Protein Ubiquitination Protein K11-linked Deubiquitination Protein K48-linked Deubiquitination Golgi Reassembly
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)
Protein-Protein Interactions		25 interactors: ABCF3 C2orf73 C9orf78 CASK CCDC158 CCDC85B CCT2 CFAP36 CHKA DAPP1 FAM9B HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 MSL1 MTUS2 PDE4DIP SH3BGR SRP72 VCPIP1 WAS WASL	7 interactors: FCHSD2 SMAD9 STX5 UBC VAV2 VCP WAC
Entrez ID		9873	80124
HPRD ID		13321	15645
Ensembl ID		ENSG00000137478	ENSG00000175073
Uniprot IDs		E9PG19 O94868	Q96JH7
PDB IDs		2DL5 2DL7
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endocytosis Regulation Of Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Toxin Transport Cellular Response To Interleukin-4 Vesicle-mediated Transport Response To Interleukin-4 Regulation Of Protein Folding In Endoplasmic Reticulum Protein Complex Assembly Phagocytosis Actin Filament-based Movement Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Organization Endoplasmic Reticulum Membrane Fusion Negative Regulation Of Membrane Tubulation Cerebellum Structural Organization Transport Actin Polymerization Or Depolymerization Cellular Protein Complex Assembly Zonula Adherens Maintenance Vesicle Transport Along Actin Filament Cellular Component Assembly Ephrin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Reassembly Dentinogenesis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Axon Guidance Protein Localization To Endoplasmic Reticulum Positive Regulation Of Clathrin-mediated Endocytosis Movement Of Cell Or Subcellular Component Response To Unfolded Protein Immune Response-regulating Signaling Pathway Choline Metabolic Process Golgi Inheritance Protein K11-linked Deubiquitination	Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process G1 DNA Damage Checkpoint ER To Golgi Vesicle-mediated Transport Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Histone H2B Conserved C-terminal Lysine Ubiquitination Protein Ubiquitination Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Protein Modification By Small Protein Conjugation Positive Regulation Of Cell Death Response To Stress Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Response To Organic Substance Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cellular Protein Catabolic Process DNA Damage Checkpoint Golgi Disassembly Cellular Response To DNA Damage Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Protein Metabolic Process Response To Transforming Growth Factor Beta Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Regulation Of Metabolic Process Endosomal Transport Neurotrophin TRK Receptor Signaling Pathway Retrograde Protein Transport, ER To Cytosol Apoptotic Process Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Cell Cycle Checkpoint Programmed Cell Death Regulation Of Protein Deubiquitination Protein Processing Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Cell Death Death Response To Organic Substance Protein Hexamerization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Response To Abiotic Stimulus
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