FCHSD2 and C9orf78

Number of citations of the paper that reports this interaction (PMID 18654987)
7

Data Source:
BioGRID (two hybrid)

		FCHSD2	C9orf78
Gene Name		FCH and double SH3 domains 2	chromosome 9 open reading frame 78
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)
Protein-Protein Interactions		25 interactors: ABCF3 C2orf73 C9orf78 CASK CCDC158 CCDC85B CCT2 CFAP36 CHKA DAPP1 FAM9B HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 MSL1 MTUS2 PDE4DIP SH3BGR SRP72 VCPIP1 WAS WASL	6 interactors: APP FCHSD2 MAPK11 SUPT5H TAB1 TERF2IP
Entrez ID		9873	51759
HPRD ID		13321	10803
Ensembl ID		ENSG00000137478	ENSG00000136819
Uniprot IDs		E9PG19 O94868	Q9NZ63
PDB IDs		2DL5 2DL7
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endocytosis Regulation Of Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Toxin Transport Cellular Response To Interleukin-4 Vesicle-mediated Transport Response To Interleukin-4 Regulation Of Protein Folding In Endoplasmic Reticulum Protein Complex Assembly Phagocytosis Actin Filament-based Movement Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Organization Endoplasmic Reticulum Membrane Fusion Negative Regulation Of Membrane Tubulation Cerebellum Structural Organization Transport Actin Polymerization Or Depolymerization Cellular Protein Complex Assembly Zonula Adherens Maintenance Vesicle Transport Along Actin Filament Cellular Component Assembly Ephrin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Reassembly Dentinogenesis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Axon Guidance Protein Localization To Endoplasmic Reticulum Positive Regulation Of Clathrin-mediated Endocytosis Movement Of Cell Or Subcellular Component Response To Unfolded Protein Immune Response-regulating Signaling Pathway Choline Metabolic Process Golgi Inheritance Protein K11-linked Deubiquitination	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Transcription, DNA-templated Negative Regulation Of DNA Recombination At Telomere Toll-like Receptor Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Stress-activated MAPK Cascade Regulation Of RNA Metabolic Process Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Protein Kinase Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of MAPK Activity Regulation Of Kinase Activity Activation Of Innate Immune Response Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Gene Expression Synaptic Growth At Neuromuscular Junction Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Innate Immune Response Collateral Sprouting In Absence Of Injury Positive Regulation Of Cellular Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Signal Transduction MAPK Cascade Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Regulation Of Innate Immune Response Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping
Tagcloud ?			11p 12p 17q11 6q16 9p21 9q34 af10 calm concurring cryptic del fnbp1 grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20
Tagcloud (Difference) ?			11p 12p 17q11 6q16 9p21 9q34 af10 calm concurring cryptic del fnbp1 grik2 hoxa imbalances immunophenotyping interphase inup214 leukemias lymphoblastic nup214 q11 q12 q34 q35 taf tcrb tlx3 usp20
Tagcloud (Intersection) ?