RUSC2 and SRPR

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		RUSC2	SRPR
Gene Name		RUN and SH3 domain containing 2	signal recognition particle receptor (docking protein)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Extracellular Vesicular Exosome	Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding	GTPase Activity Signal Recognition Particle Binding GTP Binding Poly(A) RNA Binding
	Biological Process	Biological_process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Gene Expression Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways			IRE1alpha activates chaperones Translation SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: DLST EGFR GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SRPR	3 interactors: RPL10A RUSC2 SSR2
Entrez ID		9853	6734
HPRD ID		18009	01645
Ensembl ID		ENSG00000198853	ENSG00000182934
Uniprot IDs		Q8N2Y8	P08240
PDB IDs			2FH5 2GO5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Metabolic Process Virion Assembly Mitotic Cell Cycle Rab Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process ER To Golgi Vesicle-mediated Transport Positive Regulation Of Nucleocytoplasmic Transport Cell Cycle Cellular Protein Localization Positive Regulation Of Cellular Metabolic Process Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of RNA Export From Nucleus Astrocyte Activation Establishment Of Protein Localization L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cytoplasmic Transport Interleukin-8 Production Activation Of Phospholipase A2 Activity Autophagy Positive Regulation Of Phospholipase A2 Activity Viral Life Cycle Response To Cobalamin Response To UV-A Regulation Of Nucleocytoplasmic Transport Response To Hydroxyisoflavone Protein Localization Membrane Organization Ras Protein Signal Transduction Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Establishment Of Protein Localization To Membrane Positive Regulation Of Intracellular Transport Intracellular Protein Transport Lysine Catabolic Process Cargo Loading Into Vesicle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Golgi Vesicle Transport Positive Regulation Of Catenin Import Into Nucleus Growth Hormone Secretion Positive Regulation Of Hydrolase Activity Regulation Of Phospholipase A2 Activity Regulation Of RNA Export From Nucleus Regulation Of Superoxide Anion Generation Positive Regulation Of Cellular Protein Metabolic Process	SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Organelle Protein Localization To Membrane Protein Targeting Protein Localization To Organelle Translation Cytoplasmic Transport Membrane Organization Intracellular Protein Transport Cellular Protein Localization Protein Transport Establishment Of Protein Localization Viral Transcription Intracellular Transport Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 shank1 sumo1 sypl1 tkt topbp1 znf668	ap2b2 ap3d1and cho correlating ddb1 dhfr displaying division doubling exposing extrinsic hamster intrinsic landscape mthfd2 ovary pca polarity principal productivity proteomics ranked rcan1 shotgun technologies tmem20 top traits transcriptomics
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 shank1 sumo1 sypl1 tkt topbp1 znf668	ap2b2 ap3d1and cho correlating ddb1 dhfr displaying division doubling exposing extrinsic hamster intrinsic landscape mthfd2 ovary pca polarity principal productivity proteomics ranked rcan1 shotgun technologies tmem20 top traits transcriptomics
Tagcloud (Intersection) ?