RUSC2 and RAB1A

Number of citations of the paper that reports this interaction (PMID 15796781)
3

Data Source:
BioGRID (two hybrid, pull down)

		RUSC2	RAB1A
Gene Name		RUN and SH3 domain containing 2	RAB1A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Extracellular Vesicular Exosome	Golgi Membrane Early Endosome Endoplasmic Reticulum Membrane Cytosol Melanosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Biological_process	Autophagic Vacuole Assembly Mitotic Cell Cycle Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Cilium Assembly Defense Response To Bacterium Vesicle Transport Along Microtubule Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process
Pathways			Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: DLST EGFR GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SRPR	28 interactors: ADCK1 CAPNS1 CDKN1A CHM CHML CREB1 FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SYT5 TBC1D17 USO1 ZNF593
Entrez ID		9853	5861
HPRD ID		18009	01538
Ensembl ID		ENSG00000198853	ENSG00000138069
Uniprot IDs		Q8N2Y8	B7Z8M7 P62820 Q5U0I6
PDB IDs			2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Protein Metabolic Process Virion Assembly Mitotic Cell Cycle Rab Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Alkanesulfonate Metabolic Process ER To Golgi Vesicle-mediated Transport Positive Regulation Of Nucleocytoplasmic Transport Cell Cycle Cellular Protein Localization Positive Regulation Of Cellular Metabolic Process Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Positive Regulation Of RNA Export From Nucleus Astrocyte Activation Establishment Of Protein Localization L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Cytoplasmic Transport Interleukin-8 Production Activation Of Phospholipase A2 Activity Autophagy Positive Regulation Of Phospholipase A2 Activity Viral Life Cycle Response To Cobalamin Response To UV-A Regulation Of Nucleocytoplasmic Transport Response To Hydroxyisoflavone Protein Localization Membrane Organization Ras Protein Signal Transduction Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Superoxide Anion Generation Establishment Of Protein Localization To Membrane Positive Regulation Of Intracellular Transport Intracellular Protein Transport Lysine Catabolic Process Cargo Loading Into Vesicle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Golgi Vesicle Transport Positive Regulation Of Catenin Import Into Nucleus Growth Hormone Secretion Positive Regulation Of Hydrolase Activity Regulation Of Phospholipase A2 Activity Regulation Of RNA Export From Nucleus Regulation Of Superoxide Anion Generation Positive Regulation Of Cellular Protein Metabolic Process	Protein Geranylgeranylation Protein Prenylation Positive Regulation Of Catalytic Activity Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Mitotic Cell Cycle Regulation Of GTPase Activity Membrane Fusion Positive Regulation Of Metabolic Process Protein Transport Establishment Of Protein Localization Visual Perception Sensory Perception Of Light Stimulus Slow Endocytic Recycling Riboflavin Biosynthetic Process FMN Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Membrane Organization Positive Regulation Of Microtubule Plus-end Binding Golgi Vesicle Docking Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cell Cycle Positive Regulation Of Cell Cycle Arrest Cellular Process Positive Regulation Of NAD(P)H Oxidase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Cycle Apoptotic Process Protein Localization Vesicle-mediated Transport Programmed Cell Death Signal Transduction In Response To DNA Damage Establishment Of Localization In Cell Mitotic DNA Damage Checkpoint Cell Death Death Intestinal Epithelial Cell Maturation Riboflavin Metabolic Process Regulation Of Cell Cycle Arrest Intracellular Transport Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint
Tagcloud ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 shank1 sumo1 sypl1 tkt topbp1 znf668	added become broadly characterises eevs enveloped exploits facilitating golgi growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping
Tagcloud (Difference) ?		akap6 atf7 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 shank1 sumo1 sypl1 tkt topbp1 znf668	added become broadly characterises eevs enveloped exploits facilitating golgi growing gtpase highlighting ievs immunofluorescence imvs list maintenance mature numerous optimal proviral refined replication require stranded vaccinia vacv virions wrapping
Tagcloud (Intersection) ?