CDK11B and CCNL2

Number of citations of the paper that reports this interaction (PMID 14623875)
20

Data Source:
HPRD (in vivo)

		CDK11B	CCNL2
Gene Name		cyclin-dependent kinase 11B	cyclin L2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Nucleolus Nuclear Speck Cell Junction Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Protein Kinase Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Mitotic Nuclear Division Cell Proliferation Regulation Of MRNA Processing Regulation Of Cell Cycle	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing
Pathways		G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AP2M1 CASP1 CASP3 CASP8 CCND3 CCNL2 EIF3F KAT7 MSN PAK1 PIN1 RANBP9 RPS27A TCEA2 TH TPPP URM1 YWHAB YWHAE YWHAG YWHAQ YWHAZ	6 interactors: CDK11B DYRK1A POLR2A RUNDC3A SRSF2 SRSF7
Entrez ID		984	81669
HPRD ID		08909	10815
Ensembl ID		ENSG00000248333	ENSG00000221978
Uniprot IDs		P21127	Q96S94
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Organelle Organization Protein Targeting Positive Regulation Of Intracellular Transport Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Regulation Of Cellular Component Organization Regulation Of Protein Localization Membrane Organization Intracellular Protein Transport Positive Regulation Of Signal Transduction Regulation Of Organelle Organization Immune System Process Neurotrophin TRK Receptor Signaling Pathway Cellular Protein Localization Neurotrophin Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Intracellular Transport Regulation Of Cellular Localization Regulation Of Catalytic Activity Hippo Signaling Regulation Of Apoptotic Process Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Positive Regulation Of Transport Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Response To Organic Substance Regulation Of Cell Death Regulation Of Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus	Regulation Of MRNA Processing Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Termination Of RNA Polymerase II Transcription RNA Splicing Regulation Of Nitrogen Compound Metabolic Process MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Metabolic Process RNA Processing RNA 3'-end Processing Nuclear Export MRNA Transport Transcription, RNA-templated RNA Transport RNA Localization Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Guanylate Cyclase Activity Positive Regulation Of CGMP Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of CGMP Metabolic Process Negative Regulation Of RNA Splicing Regulation Of CGMP Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Deacetylation Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of CGMP Metabolic Process 7-methylguanosine MRNA Capping PiRNA Metabolic Process Positive Regulation Of RNA Splicing 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Regulation Of Signal Transduction By P53 Class Mediator Peptidyl-threonine Phosphorylation Positive Regulation Of Viral Transcription Cytoplasmic Transport Positive Regulation Of Lyase Activity Regulation Of Protein Deacetylation Mitotic Cell Cycle
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