RB1CC1 and CALCOCO2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RB1CC1	CALCOCO2
Gene Name		RB1-inducible coiled-coil 1	calcium binding and coiled-coil domain 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Nuclear Membrane Pre-autophagosomal Structure Membrane ATG1/UKL1 Signaling Complex ULK1-ATG13-FIP200 Complex	Nucleus Cytoplasm Golgi Apparatus Cytoskeleton Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Autophagic Vacuole Assembly Liver Development Positive Regulation Of Protein Phosphorylation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle JNK Cascade Heart Development Regulation Of Autophagy Positive Regulation Of Cell Size Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	Viral Process Response To Interferon-gamma
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CALCOCO2 EXOC1 GABARAP PTK2 PTK2B RFWD2 TBKBP1 UBC VHL	143 interactors: ABLIM1 ADSL AES AKAP17A AMMECR1 AP5B1 APEX2 ARHGEF39 ARHGEF5 ARNT2 BAHD1 BCL6B BEX2 C20orf195 CBX8 CCDC185 CCDC33 CCNH CEP57L1 CHCHD3 CPNE7 CWF19L2 DAXX DAZAP2 DBNDD2 DCTN4 DCX DDIT4L DDX6 DOCK2 DUSP12 DUSP26 EEF1E1 ENKD1 EXOSC5 FAM107A FAM161A FAM168A FAM189A2 FAM90A1 FARS2 FASTK FBF1 FBXL18 FKBPL FXR2 GABARAPL1 GABARAPL2 GATAD2B GEMIN4 GIT2 GLYCTK HDAC7 HOXB9 IKBKG KANSL1 KAT7 KLHL42 LENG1 LGALS8 LIMS2 LITAF LMF2 LMO2 LMO4 LNX1 LONRF1 LSM4 MAGOHB MAVS MCM10 METTL17 MID2 MOS MTPAP MVP MXI1 MYO6 NAA10 NDN NFU1 ORC5 PAPD4 PCGF1 PEF1 PEG10 PFDN5 PHF1 PIAS4 POLI PPP1R18 PRKAB2 PRPF31 PSMA1 PSME4 PTBP1 PTBP2 RABL6 RB1CC1 RBM15 RHPN1 RIN1 RNF11 RPA2 RPL9 RPS27A RTN4IP1 RTP5 SDCBP SHC1 SLC15A3 SMARCD1 SMCP SNRPB SPATA24 SRI STK16 TAX1BP1 TBC1D22B TBK1 TBRG4 TCEB3B TCL1A TEKT3 TP53RK TRAF2 TRAF4 TRAF6 UBAC2 UBB UBC VARS VPS72 ZC2HC1C ZNF101 ZNF205 ZNF337 ZNF408 ZNF426 ZNF451 ZNF564 ZNF581 ZNF638
Entrez ID		9821	10241
HPRD ID		06019	06846
Ensembl ID		ENSG00000023287	ENSG00000136436
Uniprot IDs		Q8TDY2	Q13137
PDB IDs			3VVV 3VVW 4GXL 4HAN
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Response To Stress Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Signal Complex Assembly Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Regulation Of Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Ubiquitination Immune Response Defense Response Regulation Of Proteolysis Peptidyl-tyrosine Autophosphorylation Regulation Of Phosphatidylinositol 3-kinase Activity Response To Hypoxia Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Lipid Kinase Activity DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Negative Regulation Of Apoptotic Process Signal Transduction Involved In Cell Cycle Checkpoint Negative Regulation Of Programmed Cell Death Endothelial Cell Migration Apoptotic Process Negative Regulation Of Cell Death Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Programmed Cell Death Positive Regulation Of Cell Cycle Arrest Cell Death DNA Damage Response, Signal Transduction By P53 Class Mediator Death Response To Abiotic Stimulus Epithelial Cell Migration Positive Regulation Of Cellular Protein Metabolic Process Epithelium Migration Signal Transduction In Response To DNA Damage Immune System Process Positive Regulation Of Protein Kinase Activity Mitotic DNA Damage Checkpoint	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Type I Interferon Production MRNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Toll-like Receptor 4 Signaling Pathway Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter JNK Cascade Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Protein Modification By Small Protein Conjugation Activation Of MAPK Activity Activation Of Innate Immune Response Positive Regulation Of Intracellular Signal Transduction Regulation Of Signaling Positive Regulation Of Protein Modification Process Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Type I Interferon Production Activation Of NF-kappaB-inducing Kinase Activity Protein Ubiquitination Toll-like Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity G1/S Transition Of Mitotic Cell Cycle Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint
Tagcloud ?		bag3 broiler chicken chickens clusters cytoskeleton degs depth differentially discovered enrichment exact exploited fully gallus heat hsp25 hsph1 hunger id1 leg microarrays modules networks pdk qrt suffering thermoregulation yellow	ad astrocytes atg atgs autophagic autophagy avs beneficial brains clear clearance enhancement expected facilitating flux hippocampal impairment lc3 localized microglia mouse ndp52 p62 phosphorylated plaques reflecting sqstm1 tau vesicles
Tagcloud (Difference) ?		bag3 broiler chicken chickens clusters cytoskeleton degs depth differentially discovered enrichment exact exploited fully gallus heat hsp25 hsph1 hunger id1 leg microarrays modules networks pdk qrt suffering thermoregulation yellow	ad astrocytes atg atgs autophagic autophagy avs beneficial brains clear clearance enhancement expected facilitating flux hippocampal impairment lc3 localized microglia mouse ndp52 p62 phosphorylated plaques reflecting sqstm1 tau vesicles
Tagcloud (Intersection) ?