CD63 and CD82

Number of citations of the paper that reports this interaction (PMID 9759843)
30

Data Source:
HPRD (in vivo)

		CD63	CD82
Gene Name		CD63 molecule	CD82 molecule
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Endosome Membrane Platelet Dense Granule Membrane Intrinsic Component Of Plasma Membrane Late Endosome Membrane Endosome Lumen Melanosome Extracellular Vesicular Exosome Multivesicular Body, Internal Vesicle	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Platelet Degranulation Cell-matrix Adhesion Blood Coagulation Protein Transport Cell Migration Platelet Activation Cellular Protein Localization Endosome To Melanosome Transport Pigment Granule Maturation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Rubidium Ion Transport Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS			Hemostatic factors and hematological phenotypes ( 22443383)
Protein-Protein Interactions		13 interactors: AP4M1 CD82 CD9 HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SRF TIMP1 VKORC1	21 interactors: CANX CD19 CD4 CD63 EGFR ERBB2 ERBB3 HBEGF HLA-DMA HLA-DMB HLA-DRA IGSF8 ITGA3 ITGA4 ITGA6 ITGB1 ITGB2 LRP1 NUP88 PTGFRN VANGL1
Entrez ID		967	3732
HPRD ID		01121	09004
Ensembl ID		ENSG00000135404
Uniprot IDs		P08962	P27701
PDB IDs
Enriched GO Terms of Interacting Partners?		Wound Healing Response To Wounding Blood Coagulation Positive Regulation Of Extracellular Vesicular Exosome Assembly Hemostasis Peptide Antigen Assembly With MHC Class II Protein Complex Regulation Of Extracellular Vesicular Exosome Assembly MHC Class II Protein Complex Assembly Regulation Of Body Fluid Levels Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Organelle Assembly Platelet Activation Cell Junction Assembly Cellular Component Assembly Regulation Of Cell Adhesion Positive Regulation Of Cell-cell Adhesion Myoblast Differentiation Cell Activation Positive Regulation Of Exocytosis Positive Regulation Of Cellular Component Biogenesis Response To Stress Basophil Degranulation Contractile Actin Filament Bundle Assembly Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Exocytosis Platelet Degranulation Response To Stimulus Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Basophil Activation Polysaccharide Assembly With MHC Class II Protein Complex Myoblast Development Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Negative Regulation Of Beta-amyloid Clearance Negative Regulation Of Trophoblast Cell Migration Cell-cell Junction Assembly Secretion By Cell Establishment Of Localization In Cell Odontogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Regulation Of Exocytosis Immune System Process Striated Muscle Cell Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Positive Regulation Of Transcription By Glucose	Regulation Of Immune Response Immune System Process Regulation Of Immune System Process Positive Regulation Of Cell Adhesion Wound Healing Regulation Of Cell Adhesion Cell-matrix Adhesion Immune Response-regulating Signaling Pathway Response To Wounding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Assembly Cell-substrate Adhesion Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Locomotion Integrin-mediated Signaling Pathway Immune Response Phosphatidylinositol-mediated Signaling Movement Of Cell Or Subcellular Component Single Organismal Cell-cell Adhesion Innate Immune Response Epidermal Growth Factor Receptor Signaling Pathway Cell Migration Cell Adhesion ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Developmental Process Cell Motility Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Cell-cell Adhesion Response To Fibroblast Growth Factor Response To Stress Regulation Of Peptidyl-tyrosine Phosphorylation Defense Response Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Neurotrophin TRK Receptor Signaling Pathway Heterotypic Cell-cell Adhesion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cellular Extravasation Cell Activation Leukocyte Migration Neurotrophin Signaling Pathway Blood Coagulation Fc-epsilon Receptor Signaling Pathway Hemostasis Protein Localization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Multicellular Organismal Development
Tagcloud ?		acquire apply candidates catabolic cathepsin cathepsins colocalization compartments documents endosomal eventually follows golgi gun hete limp lysosomal mediator proform proteolysis scatters secretable secretory shot sorting storage supposed triggers unstimulated	additionally connexin32 contributes cx32 downregulated downregulation frequently hcc hepatocellular imply inhibiting invasion investigations kai1 metastasis negatively nude poor progresses promising rapidly recurrence repressed restoration suppress suppressor thereby upregulating vascular
Tagcloud (Difference) ?		acquire apply candidates catabolic cathepsin cathepsins colocalization compartments documents endosomal eventually follows golgi gun hete limp lysosomal mediator proform proteolysis scatters secretable secretory shot sorting storage supposed triggers unstimulated	additionally connexin32 contributes cx32 downregulated downregulation frequently hcc hepatocellular imply inhibiting invasion investigations kai1 metastasis negatively nude poor progresses promising rapidly recurrence repressed restoration suppress suppressor thereby upregulating vascular
Tagcloud (Intersection) ?