PDE4DIP and CCDC146

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PDE4DIP	CCDC146
Gene Name		phosphodiesterase 4D interacting protein	coiled-coil domain containing 146
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	Protein Binding Enzyme Binding
	Biological Process	Cellular Protein Complex Assembly
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933)	Response to amphetamines ( 22952603)
Protein-Protein Interactions		64 interactors: ADH1B AEN ANKRD11 ARNT2 BYSL C14orf105 C19orf66 C1orf109 CCDC146 CDC5L CDKN1A CHCHD3 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LMO4 MAPRE1 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RTP5 SCNM1 SDCBP SH2D4A SMN1 SNCA TFIP11 TK1 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26	34 interactors: CCDC136 CCNDBP1 CEP170P1 CEP44 DTNBP1 GMNN GOLGA2 KRT18 KRT19 KRT38 KRT40 MAGEA11 MAGEA6 MED4 MTUS2 NECAB2 NINL NUP62 PDE4DIP PNMA1 PSMC6 RINT1 RNF40 RPGRIP1 SPERT TFIP11 TNR TPM3 TRAF1 TRIM23 TRIM54 TSC22D4 USHBP1 VPS52
Entrez ID		9659	57639
HPRD ID		10482	11150
Ensembl ID		ENSG00000178104	ENSG00000135205
Uniprot IDs		F8WAP3 Q5VU43	Q8IYE0 Q96MS1
PDB IDs
Enriched GO Terms of Interacting Partners?		Developmental Process Response To Copper Ion RNA Metabolic Process Anatomical Structure Development Nucleobase-containing Compound Metabolic Process Regulation Of Microtubule Polymerization Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Copper Ion Response To Mineralocorticoid Cellular Nitrogen Compound Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Regulation Of Phosphorylation Response To Glucocorticoid Regulation Of JNK Cascade Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Nitrogen Compound Metabolic Process Response To Corticosteroid Regulation Of Metabolic Process Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Microtubule Polymerization Or Depolymerization Cellular Response To Epinephrine Stimulus Regulation Of Cellular Component Organization System Development Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Response To Epinephrine RNA Splicing Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Death Positive Regulation Of Transferase Activity Regulation Of Histone H3-K4 Methylation Regulation Of Kinase Activity Embryo Development Ending In Birth Or Egg Hatching MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Intracellular Signal Transduction	Cell Cycle Viral Process Mitotic Cell Cycle Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Negative Regulation Of Axon Extension Involved In Regeneration Golgi To Plasma Membrane CFTR Protein Transport Spliceosomal Complex Disassembly
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