PDE4DIP and PPP1R18

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PDE4DIP	PPP1R18
Gene Name		phosphodiesterase 4D interacting protein	protein phosphatase 1, regulatory subunit 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril	Cytoplasm Cytoskeleton
	Molecular Function	Protein Binding Enzyme Binding	Actin Binding Phosphatase Binding
	Biological Process	Cellular Protein Complex Assembly
Pathways
Drugs
Diseases
GWAS		Capecitabine sensitivity ( 22864933)
Protein-Protein Interactions		64 interactors: ADH1B AEN ANKRD11 ARNT2 BYSL C14orf105 C19orf66 C1orf109 CCDC146 CDC5L CDKN1A CHCHD3 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GFI1B GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT18 KRT31 LAMTOR3 LENG1 LMO4 MAPRE1 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RTP5 SCNM1 SDCBP SH2D4A SMN1 SNCA TFIP11 TK1 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26	37 interactors: CALCOCO2 CARD9 CCDC102B CCDC136 CCDC155 CCDC57 DES FAM9B FSD2 GOLGA2 HOMER3 KCTD9 KRT13 KRT15 KRT19 KRT31 KRT40 LZTS2 MID2 MTUS2 NEFL PDE4DIP PPP1CA PPP1CC SPDL1 SPERT STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM69 TSGA10 VPS52
Entrez ID		9659	170954
HPRD ID		10482	11172
Ensembl ID		ENSG00000178104	ENSG00000146112
Uniprot IDs		F8WAP3 Q5VU43	Q6NYC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Developmental Process Response To Copper Ion RNA Metabolic Process Anatomical Structure Development Nucleobase-containing Compound Metabolic Process Regulation Of Microtubule Polymerization Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Copper Ion Response To Mineralocorticoid Cellular Nitrogen Compound Metabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cell Death Regulation Of Phosphorylation Response To Glucocorticoid Regulation Of JNK Cascade Activation Of MAPKK Activity Positive Regulation Of Protein Kinase Activity Nitrogen Compound Metabolic Process Response To Corticosteroid Regulation Of Metabolic Process Regulation Of Microtubule-based Process Negative Regulation Of Microtubule Polymerization Negative Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Regulation Of Microtubule Polymerization Or Depolymerization Cellular Response To Epinephrine Stimulus Regulation Of Cellular Component Organization System Development Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Response To Epinephrine RNA Splicing Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Death Positive Regulation Of Transferase Activity Regulation Of Histone H3-K4 Methylation Regulation Of Kinase Activity Embryo Development Ending In Birth Or Egg Hatching MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Intracellular Signal Transduction	Cellular Component Assembly Glycogen Metabolic Process Cell Cycle Polysaccharide Metabolic Process Negative Regulation Of Viral Release From Host Cell Cytoskeleton Organization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Triglyceride Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Viral Transcription Innate Immune Response Entrainment Of Circadian Clock By Photoperiod Regulation Of Viral Release From Host Cell Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process Protein Ubiquitination Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Energy Reserve Metabolic Process Organelle Organization Cellular Protein Complex Assembly Protein Modification By Small Protein Conjugation Regulation Of Protein Binding Protein K63-linked Ubiquitination Cellular Macromolecular Complex Assembly Protein Trimerization Establishment Of Chromosome Localization Protein Complex Assembly Embryonic Digestive Tract Development Spliceosomal Complex Disassembly Chromosome Localization To Nuclear Envelope Involved In Synapsis Regulation Of Cellular Response To Growth Factor Stimulus Organelle Localization Cellular Localization Cell Division Regulation Of Extrinsic Apoptotic Signaling Pathway Establishment Of Localization In Cell Synapsis Response To Organic Substance Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Homologous Chromosome Segregation Single Organism Reproductive Process Chromosome Segregation Negative Regulation Of Interleukin-2 Secretion Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Ectodermal Digestive Tract Development Cellular Carbohydrate Metabolic Process Positive Regulation Of Protein Binding Regulation Of Viral Transcription
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