SCAMP1 and SNAP23

Number of citations of the paper that reports this interaction (PMID 12124380)
16

Data Source:
HPRD (in vivo)

		SCAMP1	SNAP23
Gene Name		secretory carrier membrane protein 1	synaptosomal-associated protein, 23kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Integral Component Of Membrane Clathrin-coated Vesicle Synaptic Vesicle Membrane Zymogen Granule Membrane Recycling Endosome Membrane	Nucleoplasm Cytoplasm Plasma Membrane Focal Adhesion SNARE Complex Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Synapse Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Exocytosis Post-Golgi Vesicle-mediated Transport Endocytosis Protein Transport	Histamine Secretion By Mast Cell Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Membrane Membrane Organization Membrane Fusion
Pathways			Translocation of GLUT4 to the plasma membrane trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339)
Protein-Protein Interactions		13 interactors: EGFR EPS15 FAM208B ITSN1 KRTAP13-1 SCAMP2 SLC9A7 SNAP23 SNAP25 SYNRG TP53 UBE3A ZMIZ2	34 interactors: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX2 STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP5 VAMP7 VAMP8 WASH2P
Entrez ID		9522	8773
HPRD ID		06072	03962
Ensembl ID		ENSG00000085365	ENSG00000092531
Uniprot IDs		O15126	A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Cellular Localization Synaptic Vesicle Priming Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Vesicle Transport Establishment Of Protein Localization Membrane Organization Transport Protein Localization Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Endocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Golgi Vesicle Transport Negative Regulation Of ERBB Signaling Pathway Protein Transport Vesicle Fusion Cellular Response To Drug Synaptic Vesicle Exocytosis Rhythmic Process Positive Regulation Of Intracellular Signal Transduction Intracellular Transport Establishment Of Organelle Localization Cellular Protein Complex Assembly Alkanesulfonate Metabolic Process Sperm Entry Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Organelle Fusion Positive Regulation Of Protein Kinase B Signaling Regulation Of ERBB Signaling Pathway Response To Osmotic Stress Positive Regulation Of Reactive Oxygen Species Metabolic Process Organelle Localization Regulation Of Fibroblast Proliferation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Regulation Of Circadian Rhythm Negative Regulation Of Macromitophagy Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Oligodendrocyte Apoptotic Process Astrocyte Activation Neurotransmitter Secretion Positive Regulation Of Synaptic Transmission Regulation Of Signaling Ovulation Cycle Negative Regulation Of Helicase Activity	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle Organization Vesicle-mediated Transport Establishment Of Localization In Cell Exocytosis Cellular Localization Protein Transport Membrane Organization Establishment Of Protein Localization Intracellular Transport Secretion By Cell Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Docking Membrane Docking Secretion Protein Localization Neurotransmitter Secretion Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Synaptic Vesicle Exocytosis Neurotransmitter Transport Synaptic Vesicle Transport Golgi Vesicle Transport Transport Establishment Of Vesicle Localization Vesicle Localization Cellular Protein Localization SNARE Complex Assembly Regulation Of Exocytosis Establishment Of Organelle Localization Organelle Organization Regulation Of Cellular Localization Cell-cell Signaling Organelle Localization Synaptic Transmission Regulation Of Secretion Regulation Of Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Positive Regulation Of Synaptic Transmission Regulation Of Synaptic Vesicle Priming Positive Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Positive Regulation Of Transport Neutrophil Degranulation Regulation Of Cellular Component Organization Golgi To Plasma Membrane Transport Regulation Of Synaptic Transmission
Tagcloud ?		adaptins adaptor ap1 arabidopsis compartment dihydrophobic dileucine ekqtll export golgi indispensible inositol interacted localize motif prevacuolar relocation rerouted separated subcellular terminus tgn thaliana tonoplast transported transporter1 vacuolar vacuole vit1	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Difference) ?		adaptins adaptor ap1 arabidopsis compartment dihydrophobic dileucine ekqtll export golgi indispensible inositol interacted localize motif prevacuolar relocation rerouted separated subcellular terminus tgn thaliana tonoplast transported transporter1 vacuolar vacuole vit1	apical brevin brevins cellubrevin clostridial codistributed cryosections exocytosis exocytotic immunogold insensitive maleimide nem neurotoxin neurotoxins nsf nts proteolyze snare snares syntaxin tent tetanus ti ultrathin vamp vesicle
Tagcloud (Intersection) ?