ACY1 and NUDT1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ACY1	NUDT1
Gene Name		aminoacylase 1	nudix (nucleoside diphosphate linked moiety X)-type motif 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extracellular Vesicular Exosome	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Extracellular Vesicular Exosome
	Molecular Function	Aminoacylase Activity Metallopeptidase Activity Metal Ion Binding	GTPase Activity 8-oxo-7,8-dihydroguanosine Triphosphate Pyrophosphatase Activity SnoRNA Binding 8-oxo-7,8-dihydrodeoxyguanosine Triphosphate Pyrophosphatase Activity GTP Diphosphatase Activity Metal Ion Binding ATP Diphosphatase Activity M7G(5')pppN Diphosphatase Activity
	Biological Process	Proteolysis Cellular Amino Acid Metabolic Process Xenobiotic Metabolic Process Small Molecule Metabolic Process	Purine Nucleotide Catabolic Process DGTP Catabolic Process DNA Repair Response To Oxidative Stress Nucleobase-containing Small Molecule Catabolic Process DNA Protection Small Molecule Metabolic Process DATP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process
Pathways		Aflatoxin activation and detoxification Biological oxidations Metabolic disorders of biological oxidation enzymes Defective ACY1 causes encephalopathy
Drugs		L-Aspartic Acid
Diseases
GWAS			Schizophrenia ( 22688191)
Protein-Protein Interactions		6 interactors: APP NPM1 NUDT1 POT1 TERF1 TTC1	1 interactors: ACY1
Entrez ID		95	4521
HPRD ID		00092	02634
Ensembl ID		ENSG00000243989	ENSG00000106268
Uniprot IDs		Q03154	P36639
PDB IDs		1Q7L	1IRY 3Q93 3ZR0 3ZR1
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Catalytic Activity Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Transferase Activity DNA Metabolic Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Telomere Maintenance Cell Aging Regulation Of Cell Cycle Process Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of DNA Strand Elongation Regulation Of Endoribonuclease Activity Regulation Of EIF2 Alpha Phosphorylation By DsRNA Positive Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication DNA Protection Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cellular Component Assembly Regulation Of Microtubule Cytoskeleton Organization Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening DGTP Catabolic Process DATP Catabolic Process Regulation Of Ribonuclease Activity Regulation Of Endodeoxyribonuclease Activity Telomere Formation Via Telomerase Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Microtubule-based Process Negative Regulation Of Cellular Metabolic Process Telomere Maintenance Via Telomere Shortening DGTP Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Chromosome Organization Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Mitotic Cell Cycle Phase Transition	Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus
Tagcloud ?		acylamino aminoacylase aminohydrolase approximate assignment autosomal chromosome chromosomes conserved electrophoretic eliminating galactosidase gangliosidosis glb1 gm1 hamster hybrids inbred linkage mammals map q21 segment segregating somatic tf transferrin translocations
Tagcloud (Difference) ?		acylamino aminoacylase aminohydrolase approximate assignment autosomal chromosome chromosomes conserved electrophoretic eliminating galactosidase gangliosidosis glb1 gm1 hamster hybrids inbred linkage mammals map q21 segment segregating somatic tf transferrin translocations
Tagcloud (Intersection) ?