BMF and BCL2A1

Number of citations of the paper that reports this interaction (PMID 15694340)
428

Data Source:
BioGRID (unspecified method)

		BMF	BCL2A1
Gene Name		Bcl2 modifying factor	BCL2-related protein A1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Mitochondrial Outer Membrane Cytosol Plasma Membrane Myosin Complex	Mitochondrial Outer Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity BH Domain Binding
	Biological Process	Apoptotic Process Positive Regulation Of Protein Homooligomerization Anoikis Positive Regulation Of Release Of Cytochrome C From Mitochondria Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Apoptotic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Programmed Cell Death Activation of BH3-only proteins BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS		Dehydroepiandrosterone sulphate levels ( 21533175) Ewing sarcoma ( 22327514)
Protein-Protein Interactions		15 interactors: BCL2 BCL2A1 BCL2L1 BCL2L2 CXCL9 DYNLL1 DYNLL2 MAPK8 MCL1 MYO5A NNMT REL SEC14L4 TCF12 TFIP11	15 interactors: APP BAD BAK1 BAX BBC3 BCL2L11 BID BIK BMF BOK FAM9B GRB2 HRK NR4A1 PMAIP1
Entrez ID		90427	597
HPRD ID		05881	03034
Ensembl ID		ENSG00000104081	ENSG00000140379
Uniprot IDs		Q96LC9	Q16548
PDB IDs			2VM6 3I1H 3MQP
Enriched GO Terms of Interacting Partners?		Intrinsic Apoptotic Signaling Pathway Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Apoptotic Process Positive Regulation Of Mitochondrion Organization Regulation Of Signal Transduction Programmed Cell Death Cell Death Death Regulation Of Cell Death Negative Regulation Of Anoikis Regulation Of Signaling Regulation Of Anoikis Positive Regulation Of Intracellular Transport Positive Regulation Of Signal Transduction Intracellular Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Death Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Mitochondrial Changes Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Immune System Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Cellular Localization Regulation Of Neuron Death Cellular Response To Stimulus Regulation Of Establishment Of Protein Localization Response To Stimulus Response To Organic Substance Response To Cytokine Melanin Metabolic Process Positive Regulation Of Transport	Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Mitochondrion Organization Positive Regulation Of Protein Oligomerization Regulation Of Mitochondrion Organization Regulation Of Protein Oligomerization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Protein Homooligomerization Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Apoptotic Mitochondrial Changes Positive Regulation Of Organelle Organization Apoptotic Process Positive Regulation Of Peptidase Activity Programmed Cell Death Cell Death Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Protein Complex Assembly Activation Of Cysteine-type Endopeptidase Activity Intrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Zymogen Activation Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Endopeptidase Activity Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Peptidase Activity Positive Regulation Of Endopeptidase Activity Release Of Cytochrome C From Mitochondria Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Proteolysis Regulation Of Membrane Permeability Positive Regulation Of Cellular Component Biogenesis Regulation Of Protein Complex Assembly Apoptotic Signaling Pathway Regulation Of Organelle Organization Regulation Of Apoptotic Process Regulation Of Proteolysis Protein Processing Positive Regulation Of Intracellular Transport Regulation Of Cell Death Mitochondrial Membrane Organization Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Tagcloud ?		70z bcgf begin bpa call chromatographic die discrete etc glycoproteins glycosylated hcgf helper heterogeneously ig implying lymphokine lymphokines mcgf mildly permeation psf purifies purify splenic supernatants synthesize variously wehi	aims apoptotic bax brdu cdk1 cdk4 changed cyclind1 cytometer explored facscan immunoblotting incorporation insulin manners obatoclax oncogene osteoblasts osteoclast poorly precursors promoted promotes remarkably suppressing treating ultimately
Tagcloud (Difference) ?		70z bcgf begin bpa call chromatographic die discrete etc glycoproteins glycosylated hcgf helper heterogeneously ig implying lymphokine lymphokines mcgf mildly permeation psf purifies purify splenic supernatants synthesize variously wehi	aims apoptotic bax brdu cdk1 cdk4 changed cyclind1 cytometer explored facscan immunoblotting incorporation insulin manners obatoclax oncogene osteoblasts osteoclast poorly precursors promoted promotes remarkably suppressing treating ultimately
Tagcloud (Intersection) ?