STX16 and STX6

Number of citations of the paper that reports this interaction (PMID 11839770)
115

Data Source:
HPRD (in vivo)

		STX16	STX6
Gene Name		syntaxin 16	syntaxin 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleolus Cytoplasm Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Cytosol Focal Adhesion Endomembrane System Membrane Integral Component Of Membrane SNARE Complex Golgi Cisterna Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Golgi Membrane Early Endosome Golgi Apparatus Trans-Golgi Network Plasma Membrane Integral Component Of Membrane Clathrin-coated Vesicle SNARE Complex Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Vesicle Fusion Retrograde Transport, Endosome To Golgi Vesicle Docking Golgi Ribbon Formation	Intracellular Protein Transport Vesicle Fusion Endosome Organization Regulation Of Protein Localization Retrograde Transport, Endosome To Golgi Golgi Vesicle Transport Golgi Ribbon Formation
Pathways
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 20838585)	Progressive supranuclear palsy ( 21685912)
Protein-Protein Interactions		10 interactors: MEOX2 NAPB PTPN12 STX4 STX6 VAMP3 VAMP4 VAMP5 VPS45 VTI1A	15 interactors: EEA1 GOPC GOSR2 MARCH2 NAPB PSMA3 PTPN9 SNAP23 SNAP29 STX16 STX4 STX7 VAMP4 VPS11 VPS18
Entrez ID		8675	10228
HPRD ID		04718	07231
Ensembl ID		ENSG00000124222	ENSG00000135823
Uniprot IDs		B4DJX9 O14662	B4DR17 O43752
PDB IDs			2NPS
Enriched GO Terms of Interacting Partners?		Membrane Fusion Vesicle Fusion Organelle Fusion Vesicle Organization Golgi Ribbon Formation SNARE Complex Assembly Vesicle-mediated Transport Membrane Organization Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Establishment Of Localization In Cell Exocytosis Cellular Protein Localization Protein Transport Establishment Of Protein Localization Cellular Localization Intracellular Transport Endomembrane System Organization Secretion By Cell Protein Localization Retrograde Transport, Endosome To Golgi Secretion Golgi Organization Vesicle Docking Membrane Docking Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Golgi To Plasma Membrane Protein Transport Neurotransmitter Transport Endosomal Transport Golgi To Plasma Membrane Transport Transport Regulation Of Establishment Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Plasma Membrane Vesicle Docking Involved In Exocytosis Cellular Protein Complex Assembly Establishment Of Protein Localization To Plasma Membrane Organelle Organization Positive Regulation Of Eosinophil Degranulation Skeletal Muscle Tissue Development Voluntary Musculoskeletal Movement Skeletal Muscle Organ Development Protein Localization To Plasma Membrane Cellular Macromolecular Complex Assembly SNARE Complex Disassembly Somite Specification Cytoplasmic Transport Positive Regulation Of Protein Localization To Cell Surface Golgi To Vacuole Transport	Vesicle Fusion Membrane Fusion Organelle Fusion Vesicle-mediated Transport Vesicle Organization Establishment Of Localization In Cell Membrane Organization Cellular Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Fusion To Presynaptic Membrane Transport Vesicle Docking Post-Golgi Vesicle-mediated Transport Membrane Docking Golgi Vesicle Transport Cellular Protein Localization Synaptic Vesicle Transport Intracellular Protein Transport Exocytosis Regulation Of Establishment Of Protein Localization To Plasma Membrane Organelle Organization Organelle Localization Synaptic Vesicle Exocytosis Establishment Of Vesicle Localization Golgi Ribbon Formation Vesicle Localization Secretion By Cell Regulation Of Golgi To Plasma Membrane Protein Transport Synaptic Vesicle Priming SNARE Complex Assembly Secretion Neurotransmitter Secretion Establishment Of Organelle Localization Cellular Protein Complex Assembly Regulation Of Vesicle-mediated Transport Regulation Of Neurotransmitter Levels Neurotransmitter Transport Endosomal Transport Protein Complex Assembly Vesicle Targeting Synaptic Transmission Intra-Golgi Vesicle-mediated Transport Cellular Macromolecular Complex Assembly Cellular Component Assembly Synaptic Vesicle To Endosome Fusion Cytoplasmic Sequestering Of CFTR Protein
Tagcloud ?		attachment cog cog4 cog8 defining ethylmalemide golgi gs27 initiate intermediates machinery namely oligomeric platforms redirection relocalization retrograde reveals snap29 snares sorting stx5 stx6 tethering tethers uncover vesicles vesicular vicinity	alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3
Tagcloud (Difference) ?		attachment cog cog4 cog8 defining ethylmalemide golgi gs27 initiate intermediates machinery namely oligomeric platforms redirection relocalization retrograde reveals snap29 snares sorting stx5 tethering tethers uncover vesicles vesicular vicinity	alpha5beta1 alphavbeta3 boundaries c1 cho cholesterol endosome endosomes export hamster imbalance integrins interferes niemann npc1 ovary pick rab11 re recycling res restoration restores snare syntaxin tgn transferrin tuning vamp3
Tagcloud (Intersection) ?		stx6