RFXANK and RFXAP

Number of citations of the paper that reports this interaction (PMID 10825209)
10

Data Source:
HPRD (in vitro, in vivo)

		RFXANK	RFXAP
Gene Name		regulatory factor X-associated ankyrin-containing protein	regulatory factor X-associated protein
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Intercellular Bridge	Nucleus
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Histone Deacetylase Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Ras Protein Signal Transduction Positive Regulation Of Transcription From RNA Polymerase II Promoter	Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CIITA HDAC4 HDAC5 RAF1 RFX5 RFXAP	4 interactors: EPS8 RFX5 RFXANK SMARCA4
Entrez ID		8625	5994
HPRD ID		04435	03515
Ensembl ID		ENSG00000064490	ENSG00000133111
Uniprot IDs		O14593 Q24JQ1	O00287
PDB IDs		3UXG 3V30	2KW3
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Myotube Differentiation Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Striated Muscle Cell Differentiation Histone H4 Deacetylation Osteoblast Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone H3 Deacetylation Negative Regulation Of Cellular Metabolic Process Histone H3-K9 Modification Negative Regulation Of Muscle Cell Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Myotube Differentiation Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Histone Deacetylation Regulation Of Skeletal Muscle Tissue Development Protein Deacetylation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Defense Response Negative Regulation Of Ossification Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Striated Muscle Cell Differentiation Death-inducing Signaling Complex Assembly B Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Osteoblast Differentiation Cell Activation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Striated Muscle Tissue Development Osteoblast Differentiation Negative Regulation Of Cell Differentiation Regulation Of Protein Binding Regulation Of Muscle Cell Differentiation B Cell Activation Chromatin Remodeling Immune System Process Regulation Of Transcription, DNA-templated Regulation Of Ossification Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Gene Expression, Epigenetic	Negative Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Actin Polymerization-dependent Cell Motility Ras Protein Signal Transduction DNA Methylation On Cytosine Within A CG Sequence Definitive Erythrocyte Differentiation Aortic Smooth Muscle Cell Differentiation Exit From Mitosis Glial Cell Fate Determination Methylation-dependent Chromatin Silencing Behavioral Response To Ethanol Positive Regulation By Host Of Viral Transcription Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation On Cytosine Negative Regulation Of Androgen Receptor Signaling Pathway Nucleosome Disassembly Blastocyst Hatching Rac Protein Signal Transduction Heart Trabecula Formation Lens Fiber Cell Development Vascular Smooth Muscle Cell Differentiation Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration Glial Cell Fate Commitment RNA Biosynthetic Process Small GTPase Mediated Signal Transduction Definitive Hemopoiesis Heart Trabecula Morphogenesis Blastocyst Growth Interaction With Symbiont Chromatin Silencing Lens Fiber Cell Differentiation Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of DNA Binding Epidermis Morphogenesis Histone H3 Acetylation Positive Regulation Of Viral Transcription Actin Filament Capping Trabecula Morphogenesis Embryonic Hindlimb Morphogenesis Cell Fate Determination Skin Morphogenesis RNA Metabolic Process Neural Retina Development Smooth Muscle Cell Differentiation Negative Regulation Of Actin Filament Depolymerization Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Tagcloud ?		ankra2 ankyrin deacetylases docking hdac4 hdac5 hdac9 iia lock megalin motif operate paralog preference principle proteome pxlpxi recognize recognizes repeat repeats residue rfx5 sequester serving switch tumbler uncharacterized uncover	ankyrin assembles associate associates atf1 class coactivators coimmunoprecipitation compose cooperate enhanceosome leucine mhc module nlr nlrc5 nonderepressible nucleoprotein participates promoters repeats rfx5 rfxank tight transactivates w x1 x2
Tagcloud (Difference) ?		ankra2 deacetylases docking hdac4 hdac5 hdac9 iia lock megalin motif operate paralog preference principle proteome pxlpxi recognize recognizes repeat residue sequester serving switch tumbler uncharacterized uncover	assembles associate associates atf1 class coactivators coimmunoprecipitation compose cooperate enhanceosome leucine mhc module nlr nlrc5 nonderepressible nucleoprotein participates promoters tight transactivates w x1 x2
Tagcloud (Intersection) ?		ankyrin repeats rfx5 rfxank