LRRCC1 and C14orf119

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		LRRCC1	C14orf119
Gene Name		leucine rich repeat and coiled-coil centrosomal protein 1	chromosome 14 open reading frame 119
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Centrosome Centriole	Mitochondrion
	Molecular Function
	Biological Process	Mitotic Nuclear Division Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: C14orf119 CAPNS1 FADD	1 interactors: LRRCC1
Entrez ID		85444	55017
HPRD ID		11160	16595
Ensembl ID		ENSG00000133739	ENSG00000179933
Uniprot IDs		B4DTJ0 Q9C099	Q9NWQ9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Motor Neuron Apoptotic Process Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Cellular Extravasation Necroptotic Signaling Pathway Positive Regulation Of Macrophage Differentiation Negative Regulation Of Activation-induced Cell Death Of T Cells Positive Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Activation-induced Cell Death Of T Cells Negative Regulation Of Necroptotic Process Positive Regulation Of Cell Proliferation Lymph Node Development Negative Regulation Of Necrotic Cell Death Regulation Of Necroptotic Process Positive Regulation Of T Cell Migration Regulation Of T Cell Migration Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Activated T Cell Proliferation Regulation Of Necrotic Cell Death Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Lymphocyte Migration Positive Regulation Of Interleukin-8 Production Necroptotic Process Regulation Of Activated T Cell Proliferation T Cell Homeostasis Regulation Of Type I Interferon-mediated Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Spleen Development Regulation Of T Cell Apoptotic Process Programmed Necrotic Cell Death Necrotic Cell Death Regulation Of Cell Proliferation Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Myeloid Leukocyte Differentiation Positive Regulation Of Interferon-gamma Production Negative Regulation Of Leukocyte Apoptotic Process Positive Regulation Of Tumor Necrosis Factor Production Neuron Apoptotic Process Thymus Development TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Lymphocyte Apoptotic Process Neuron Death MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway T Cell Differentiation In Thymus
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