IFITM1 and CD81

Number of citations of the paper that reports this interaction (PMID 2398277)
32

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		IFITM1	CD81
Gene Name		interferon induced transmembrane protein 1	CD81 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Vesicle Extracellular Vesicular Exosome
	Molecular Function	Receptor Signaling Protein Activity Protein Binding	Protein Binding MHC Class II Protein Complex Binding
	Biological Process	Ossification Cell Surface Receptor Signaling Pathway Negative Regulation Of Cell Proliferation Response To Virus Cytokine-mediated Signaling Pathway Negative Regulation Of Cell Migration Response To Interferon-gamma Response To Interferon-alpha Response To Interferon-beta Intracellular Signal Transduction Negative Regulation Of Viral Genome Replication Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Viral Entry Into Host Cell Regulation Of Immune Response Defense Response To Virus Type I Interferon Signaling Pathway	Activation Of MAPK Activity Phosphatidylinositol Biosynthetic Process Protein Localization Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Phosphatidylinositol Metabolic Process Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Regulation Of Cell Motility
Pathways		Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ABHD16A CD81 CR2	20 interactors: ADRB2 CD19 CD9 CSNK2B DLG5 HNRNPD IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT MYOC PTGFRN RBBP6 RNF128 SHC1 TSPAN4 VKORC1 ZBTB16
Entrez ID		8519	975
HPRD ID		05122	08924
Ensembl ID		ENSG00000185885	ENSG00000110651
Uniprot IDs		P13164	E9PJK1 P60033
PDB IDs			1G8Q 1IV5 2AVZ
Enriched GO Terms of Interacting Partners?		Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Receptor-mediated Virion Attachment To Host Cell Complement Receptor Mediated Signaling Pathway Virion Attachment To Host Cell Adhesion Of Symbiont To Host Cell Proliferation Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of B Cell Proliferation Viral Entry Into Host Cell B Cell Proliferation Entry Into Host Cell	Organ Development ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Proliferation System Development Regulation Of Immune Response Regulation Of Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Developmental Process Positive Regulation Of Ossification B Cell Differentiation Multicellular Organismal Development Anatomical Structure Development Movement Of Cell Or Subcellular Component Regulation Of Cell Motility Response To Stress Negative Regulation Of Cell Proliferation Regulation Of Locomotion Cell Activation Regulation Of Cellular Component Movement B Cell Activation Epidermal Growth Factor Receptor Signaling Pathway Tissue Development Fibroblast Growth Factor Receptor Signaling Pathway Blood Coagulation Hemostasis Positive Regulation Of Signal Transduction Innate Immune Response Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Regulation Of Ossification Stem Cell Division Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Single Organismal Cell-cell Adhesion Leukocyte Migration Fc-epsilon Receptor Signaling Pathway Cell Differentiation Bone Development Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Skeletal Muscle Hypertrophy Negative Regulation Of FasL Biosynthetic Process Zonula Adherens Assembly ERBB2-ERBB3 Signaling Pathway Mast Cell Proliferation Lymphocyte Differentiation
Tagcloud ?		altogether codon downregulation enable entire envelope envg367e evade g367 gp120 hiv immunodeficiency introduces mutate overcome p24 passages replication residue restriction stop supt1 transmembrane transmission utilized viruses vpu vpu34	000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Difference) ?		altogether codon downregulation enable entire envelope envg367e evade g367 gp120 hiv immunodeficiency introduces mutate overcome p24 passages replication residue restriction stop supt1 transmembrane transmission utilized viruses vpu vpu34	000xg calreticulin centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vdac1 vesicle
Tagcloud (Intersection) ?