CNTNAP1 and NFASC

Number of citations of the paper that reports this interaction (PMID 11839274)
43

Data Source:
HPRD (in vitro)

		CNTNAP1	NFASC
Gene Name		contactin associated protein 1	neurofascin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Paranode Region Of Axon	Intracellular Plasma Membrane Focal Adhesion Integral Component Of Membrane Paranodal Junction Node Of Ranvier Paranode Region Of Axon Axon Initial Segment Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding	Protein Binding Protein Binding Involved In Heterotypic Cell-cell Adhesion
	Biological Process	Protein Localization To Paranode Region Of Axon Cytoskeleton Organization Cell Adhesion Signal Transduction Axon Guidance Axon Cargo Transport Positive Regulation Of Signal Transduction Neuronal Action Potential Propagation Paranodal Junction Assembly Neuron Projection Morphogenesis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance	Protein Localization To Paranode Region Of Axon Axon Guidance Peripheral Nervous System Development Transmission Of Nerve Impulse Paranodal Junction Assembly Heterotypic Cell-cell Adhesion Myelination Clustering Of Voltage-gated Sodium Channels Synapse Organization Protein Localization To Juxtaparanode Region Of Axon
Pathways		Axon guidance Neurofascin interactions L1CAM interactions	Interaction between L1 and Ankyrins Axon guidance Neurofascin interactions L1CAM interactions
Drugs
Diseases
GWAS			Dental caries ( 23064961)
Protein-Protein Interactions		8 interactors: CDC42 FYN NFASC PTPRB RAC1 RHOA RTN4 SRC	10 interactors: ANK1 CNTNAP1 DCX NRCAM SCN1B SCN3B SCNN1B SDCBP SDCBP2 TNR
Entrez ID		8506	23114
HPRD ID		03825	12372
Ensembl ID		ENSG00000108797	ENSG00000163531
Uniprot IDs		P78357	B4DRH7 O94856
PDB IDs			3P3Y 3P40
Enriched GO Terms of Interacting Partners?		Axon Development Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Axon Guidance Neuron Development Regulation Of Cell Projection Organization Cell Morphogenesis Cell-cell Junction Organization Neurotrophin TRK Receptor Signaling Pathway Axonogenesis Neurotrophin Signaling Pathway Neuron Differentiation Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation T Cell Costimulation Chemotaxis Locomotion Neuron Projection Morphogenesis Anatomical Structure Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Movement Of Cell Or Subcellular Component Brain Development Head Development Generation Of Neurons Cell Migration Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Cell Motility Enzyme Linked Receptor Protein Signaling Pathway Blood Coagulation Hemostasis Cell Development Central Nervous System Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cell Morphogenesis Platelet Activation Positive Regulation Of T Cell Activation Cellular Response To Growth Factor Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Body Fluid Levels Regulation Of Phosphatidylinositol 3-kinase Activity Response To Growth Factor Leukocyte Migration Wound Healing	Axon Guidance Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Neuronal Action Potential Propagation Neuron Projection Development Nervous System Development Cell Projection Morphogenesis Cell Part Morphogenesis Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Movement Of Cell Or Subcellular Component Generation Of Neurons Neurogenesis System Development Transmission Of Nerve Impulse Cell Development Response To External Stimulus Neurological System Process Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Multicellular Organismal Development Anatomical Structure Development Membrane Depolarization During Cardiac Muscle Cell Action Potential Anatomical Structure Morphogenesis Developmental Process Cell-cell Signaling Involved In Cardiac Conduction Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Sodium Ion Transmembrane Transport Membrane Depolarization During Action Potential Regulation Of Membrane Depolarization Cardiac Muscle Cell Action Potential Cell Differentiation Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Sodium Ion Transport Monovalent Inorganic Cation Transport Central Nervous System Projection Neuron Axonogenesis Sodium Ion Transport Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cardiac Muscle Contraction Cell Migration Signaling
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