PKP4 and PDZD2

Number of citations of the paper that reports this interaction (PMID 10896674)
15

Data Source:
HPRD (in vitro, in vivo)

		PKP4	PDZD2
Gene Name		plakophilin 4	PDZ domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Cytoplasm Cytoskeleton Plasma Membrane Cell-cell Junction Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Desmosome Midbody Cell-cell Contact Zone Perinuclear Region Of Cytoplasm Spindle Midzone Mitotic Spindle	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Cell-cell Junction
	Molecular Function	Protein Binding
	Biological Process	Cell-cell Junction Assembly Cell-cell Signaling Single Organismal Cell-cell Adhesion Regulation Of Cell Adhesion Positive Regulation Of Rho GTPase Activity Positive Regulation Of Cytokinesis	Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Obesity-related traits ( 23251661) Renal cell carcinoma ( 23184150)
Protein-Protein Interactions		18 interactors: ATPAF2 CDH1 CDH2 CDH5 DSC3 DSP ERBB2IP GABARAP GOLGA2 LNX1 LZTS2 MINK1 OSGEP PAXIP1 PDZD2 PGAM1 PSEN1 TRIM23	5 interactors: BAI1 CST3 CTNND2 NRXN1 PKP4
Entrez ID		8502	23037
HPRD ID		05043	10142
Ensembl ID		ENSG00000144283	ENSG00000133401
Uniprot IDs		Q99569	O15018
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Adhesion Adherens Junction Organization Single Organismal Cell-cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Bundle Of His Cell To Purkinje Myocyte Communication Cell-cell Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cellular Component Assembly Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cellular Response To Starvation Negative Regulation Of Canonical Wnt Signaling Pathway Cardiac Muscle Cell Action Potential Involved In Contraction Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cellular Response To Nutrient Levels Response To Starvation Cardiovascular System Development Cardiac Muscle Cell Action Potential Negative Regulation Of Wnt Signaling Pathway Autophagic Vacuole Assembly Cell Junction Assembly Regulation Of Protein Ubiquitination Intermediate Filament Cytoskeleton Organization Blood Vessel Development Intermediate Filament-based Process Cellular Response To Extracellular Stimulus Regulation Of Cardiac Muscle Cell Contraction Vasculature Development Cardiac Conduction Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Stress Macroautophagy Cajal-Retzius Cell Differentiation Positive Regulation Of Histone H3-K36 Methylation Regulation Of Pentose-phosphate Shunt Beta-amyloid Formation Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Membrane Potential Organelle Organization Cytoskeleton Organization Regulation Of Wnt Signaling Pathway Execution Phase Of Apoptosis Regulation Of Heart Rate Regulation Of Cellular Component Movement Regulation Of Cardiac Muscle Contraction Threonylcarbamoyladenosine Biosynthetic Process Basal Protein Localization	Cell Adhesion Single Organismal Cell-cell Adhesion Protein Complex Assembly Involved In Synapse Maturation Negative Regulation Of Elastin Catabolic Process Negative Regulation Of Blood Vessel Remodeling Gamma-aminobutyric Acid Receptor Clustering Negative Regulation Of Collagen Catabolic Process Learning Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Gephyrin Clustering Synaptic Vesicle Clustering Regulation Of Collagen Catabolic Process Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Extracellular Matrix Disassembly Neuronal Signal Transduction N-methyl-D-aspartate Receptor Clustering Vocal Learning Negative Regulation Of Filopodium Assembly Regulation Of Blood Vessel Remodeling Postsynaptic Membrane Assembly Learning Or Memory Synapse Maturation Regulation Of Grooming Behavior Cognition Regulation Of Synaptic Transmission Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering Receptor Localization To Synapse Negative Regulation Of Multicellular Organismal Metabolic Process Presynaptic Membrane Organization Auditory Behavior Extracellular Matrix Organization Extracellular Structure Organization Negative Regulation Of Glycoprotein Metabolic Process Extracellular Fibril Organization Cerebellar Granule Cell Differentiation Vocalization Behavior Prepulse Inhibition Neuron Cell-cell Adhesion Positive Regulation Of Synapse Maturation Single-organism Behavior Negative Regulation Of Tissue Remodeling Mechanosensory Behavior Cerebellar Granular Layer Morphogenesis Response To Auditory Stimulus Regulation Of Synapse Maturation Protein Localization To Synapse Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Membrane Assembly
Tagcloud ?			1e appeared basal defect deficient depleted displayed duplexes enriched exocrine explore fasting glucose gross homozygous ins intraperitoneal islet islets morphology multi pancreatic secretion sirna tolerance twofold verify viable
Tagcloud (Difference) ?			1e appeared basal defect deficient depleted displayed duplexes enriched exocrine explore fasting glucose gross homozygous ins intraperitoneal islet islets morphology multi pancreatic secretion sirna tolerance twofold verify viable
Tagcloud (Intersection) ?