OFD1 and GPRASP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OFD1	GPRASP1
Gene Name		oral-facial-digital syndrome 1	G protein-coupled receptor associated sorting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Centriole Cytosol Cilium Microtubule Cytoskeleton Membrane Centriolar Satellite Ciliary Basal Body	Cytoplasm
	Molecular Function	Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Embryonic Body Morphogenesis Axoneme Assembly Cilium Morphogenesis Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation	Endosome To Lysosome Transport G-protein Coupled Receptor Catabolic Process
Pathways		Organelle biogenesis and maintenance Hedgehog 'off' state Assembly of the primary cilium G2/M Transition Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CCSER2 EIF6 GPRASP1 KIAA1377 LUC7L2 NME7 PLK1 RUVBL1	47 interactors: ADRB1 ADRB2 AGTR1 ATXN7 C8orf33 CALCR CHRM1 CHRM2 CHRM3 CHRM4 CHRM5 CRIP1 CXCR2 F2R F2RL1 GLP1R GLYAT GRM1 GRM5 GRM8 HGH1 HMOX2 HTR7 LAMTOR5 LRP2 MAP7D1 MLNR MTF2 OFD1 OPRD1 OPRK1 OPRL1 OPRM1 OXTR PBK PER1 PFDN1 SNAPIN STMN2 TAC3 TACR1 TACR2 TACR3 TBXA2R TFG TRAF4 VIPR1
Entrez ID		8481	9737
HPRD ID		02162	02333
Ensembl ID		ENSG00000046651	ENSG00000198932
Uniprot IDs		A6NF31 A8K2T9 E9KL37 O75665	Q5JY77
PDB IDs
Enriched GO Terms of Interacting Partners?		Microtubule-based Process Microtubule Bundle Formation Organelle Organization Microtubule Cytoskeleton Organization Activation Of APC-Cdc20 Complex Activity G-protein Coupled Receptor Catabolic Process Cellular Macromolecular Complex Assembly Mitotic Cell Cycle Process Polar Body Extrusion After Meiotic Divisions Ribonucleoprotein Complex Assembly Mitotic Cell Cycle Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Cilium Organization Mature Ribosome Assembly Cellular Component Assembly Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Metaphase/anaphase Transition Of Mitotic Cell Cycle Ribosomal Subunit Export From Nucleus Cell Cycle Process Protein Localization To Chromatin Mitotic Nuclear Division Ribonucleoprotein Complex Biogenesis Cytoskeleton Organization Histone H2A Acetylation Cellular Localization Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Chromosome Segregation	G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Synaptic Transmission Cytosolic Calcium Ion Homeostasis Regulation Of Smooth Muscle Contraction Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Response To Stimulus Cellular Metal Ion Homeostasis Cell-cell Signaling Positive Regulation Of Smooth Muscle Contraction Cellular Cation Homeostasis Cellular Ion Homeostasis Signaling Signal Transduction Metal Ion Homeostasis Cell Communication Blood Circulation Cellular Chemical Homeostasis Ion Homeostasis Response To Stimulus Neuropeptide Signaling Pathway Regulation Of Muscle Contraction G-protein Coupled Acetylcholine Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cellular Homeostasis Chemical Homeostasis Regulation Of Blood Pressure Tachykinin Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure Opioid Receptor Signaling Pathway Regulation Of Vasoconstriction Positive Regulation Of Uterine Smooth Muscle Contraction Neurological System Process Homeostatic Process Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Blood Pressure Behavior Regulation Of CAMP Biosynthetic Process Sensory Perception Of Pain Regulation Of Secretion Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Regulation Of CAMP Metabolic Process Response To Abiotic Stimulus Regulation Of Adenylate Cyclase Activity
Tagcloud ?		1x apparatus consequences depicted digital dimerization disclosed dramatically facial filaments focused golgi half homology implies imported lis1 lish localization localizations motif mutated nucleus oligomerization participate prediction solved tbl1 transducin
Tagcloud (Difference) ?		1x apparatus consequences depicted digital dimerization disclosed dramatically facial filaments focused golgi half homology implies imported lis1 lish localization localizations motif mutated nucleus oligomerization participate prediction solved tbl1 transducin
Tagcloud (Intersection) ?