GTPBP3 and PRPF3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GTPBP3	PRPF3
Gene Name		GTP binding protein 3 (mitochondrial)	pre-mRNA processing factor 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	GTPase Activity GTP Binding	Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	TRNA Modification	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CIC DCAF8 FAM60A GNE PARP11 PFKL PRPF3 PTAFR RIBC2	24 interactors: BRCA1 CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GTPBP3 NHP2L1 NKAP PCBP1 PPIH PRPF31 PRPF4 RBM39 SART3 SNIP1 TRIM39 U2AF2 USP4 WBP4 ZCCHC10
Entrez ID		84705	9129
HPRD ID		12255	07389
Ensembl ID		ENSG00000130299	ENSG00000117360
Uniprot IDs		B7Z563 Q969Y2	E7EVD1 O43395
PDB IDs			1X4Q
Enriched GO Terms of Interacting Partners?		Carbohydrate Phosphorylation N-acetylglucosamine Biosynthetic Process Fructose 1,6-bisphosphate Metabolic Process Inositol Trisphosphate Biosynthetic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly Cellular Metabolic Process Spliceosomal SnRNP Assembly Hematopoietic Stem Cell Proliferation Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Ribonucleoprotein Complex Biogenesis Metabolic Process Cochlea Morphogenesis Regulation Of Gene Expression Non-canonical Wnt Signaling Pathway Ribonucleoprotein Complex Assembly Regulation Of Protein Ubiquitination Cochlea Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone Deubiquitination Positive Regulation Of Histone H4-K16 Acetylation Outflow Tract Morphogenesis Positive Regulation Of Histone Modification Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of JUN Kinase Activity Cellular Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of JUN Kinase Activity Stem Cell Proliferation Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Signal Transduction In Response To DNA Damage RNA Biosynthetic Process Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Inner Ear Morphogenesis Negative Regulation Of Protein Ubiquitination Non-canonical Wnt Signaling Pathway Via JNK Cascade
Tagcloud ?			accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Difference) ?			accumulative assumes debilitating decades degeneration developmentally example focused hypotheses hypothesis implying interacting interrupt intriguing metabolically methodology mildly phenomenon photoreceptors principal prp31 prpc8 retina retinal rp18 snrnas splicing suboptimal ubiquitously
Tagcloud (Intersection) ?