TMEM101 and MAP4K1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TMEM101	MAP4K1
Gene Name		transmembrane protein 101	mitogen-activated protein kinase kinase kinase kinase 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Integral Component Of Membrane	Cytoplasm Membrane
	Molecular Function	Signal Transducer Activity	Protein Kinase Activity Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding MAP Kinase Kinase Kinase Kinase Activity
	Biological Process	Signal Transduction Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling	Activation Of MAPKKK Activity Protein Phosphorylation Response To Stress Activation Of JUN Kinase Activity Cell Proliferation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: MAP4K1	20 interactors: ABL1 BLNK CASP3 CRK CRKL DAPP1 DBNL EGFR GRAP2 GRB2 HCLS1 LAT LCP2 LYN MAP3K11 MAP3K7 NCK1 SHC1 SYK TMEM101
Entrez ID		84336	11184
HPRD ID		14623	03583
Ensembl ID		ENSG00000091947	ENSG00000104814
Uniprot IDs		Q96IK0	Q92918
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of MAPKKK Activity Activation Of JUN Kinase Activity Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity JNK Cascade Stress-activated MAPK Cascade Peptidyl-serine Phosphorylation Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Activation Of MAPK Activity Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Protein Autophosphorylation Positive Regulation Of MAP Kinase Activity MAPK Cascade Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Signal Transduction By Phosphorylation Regulation Of MAP Kinase Activity	Positive Regulation Of Signal Transduction Fc Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Immune System Process Positive Regulation Of Intracellular Signal Transduction Immune Response-activating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphorylation Regulation Of Immune System Process Regulation Of Protein Kinase Activity Fc-epsilon Receptor Signaling Pathway Signal Transduction Antigen Receptor-mediated Signaling Pathway Regulation Of Signal Transduction Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Innate Immune Response Intracellular Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Signaling Regulation Of MAPK Cascade Regulation Of Immune Response Cell Communication Regulation Of Signaling Positive Regulation Of Protein Metabolic Process Cell Activation Immune Response Positive Regulation Of Protein Phosphorylation Defense Response Regulation Of Intracellular Signal Transduction Response To Stress Regulation Of Cell-cell Adhesion Cellular Response To Stimulus Positive Regulation Of Phosphorylation Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Activation Of Protein Kinase Activity Positive Regulation Of MAPK Cascade Signal Transduction By Phosphorylation Regulation Of T Cell Activation Positive Regulation Of Kinase Activity Platelet Activation Positive Regulation Of Transferase Activity Regulation Of Cellular Protein Metabolic Process MAPK Cascade Cell Surface Receptor Signaling Pathway
Tagcloud ?			accelerated called cd4 chip concordantly contributing enhancer enrichment erythematosus h3k27me3 homolog hpk1 hyper ifngamma igg jmjd3 jumonji knock lupus medications overactivation overexpressing overstimulation plasmid reactivity sle striking trimethylation zeste
Tagcloud (Difference) ?			accelerated called cd4 chip concordantly contributing enhancer enrichment erythematosus h3k27me3 homolog hpk1 hyper ifngamma igg jmjd3 jumonji knock lupus medications overactivation overexpressing overstimulation plasmid reactivity sle striking trimethylation zeste
Tagcloud (Intersection) ?