RPAIN and GSTA1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPAIN	GSTA1
Gene Name		RPA interacting protein	glutathione S-transferase alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm PML Body	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Complex Binding Metal Ion Binding	Glutathione Transferase Activity
	Biological Process	DNA-dependent DNA Replication DNA Repair DNA Recombination Protein Import Into Nucleus Response To UV	Glutathione Metabolic Process Xenobiotic Metabolic Process Metabolic Process Epithelial Cell Differentiation Small Molecule Metabolic Process Glutathione Derivative Biosynthetic Process
Pathways			Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs			Glutathione S-Hydroxycysteine 2-Hydroxyethyl Disulfide N-(4-Aminobutanoyl)-S-(4-Methoxybenzyl)-L-Cysteinylglycine Glutathione Sulfonic Acid S-Benzyl-Glutathione S-Hexylglutathione
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ADH6 CDCA5 CYP17A1 GSTA1	7 interactors: APP GSTA2 LSM3 PPP2CB RPAIN ST3GAL1 YWHAE
Entrez ID		84268	2938
HPRD ID		14615	00708
Ensembl ID		ENSG00000129197
Uniprot IDs		B3KTT3 E9PDG9 Q86UA6	B7Z1F9 P08263
PDB IDs			1GSD 1GSE 1GSF 1GUH 1K3L 1K3O 1K3Y 1LBK 1PKW 1PKZ 1PL1 1PL2 1USB 1XWG 1YDK 2R3X 2R6K 3I69 3I6A 3IK9 3KTL 3L0H 3Q74 3U6V 3ZFB 3ZFL 4HJ2
Enriched GO Terms of Interacting Partners?		Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Response To Acetate Regulation Of Cohesin Localization To Chromatin Alcohol Metabolic Process Response To Fungicide Phthalate Metabolic Process Positive Regulation Of Steroid Hormone Biosynthetic Process Glucocorticoid Biosynthetic Process Response To Herbicide Response To Methylmercury Dibenzo-p-dioxin Metabolic Process Biphenyl Metabolic Process Positive Regulation Of Hormone Biosynthetic Process Mitotic Sister Chromatid Cohesion Ethanol Oxidation Regulation Of Sister Chromatid Cohesion Androgen Biosynthetic Process Glucocorticoid Metabolic Process Response To Insecticide Leydig Cell Differentiation Cellular Response To Antibiotic Small Molecule Metabolic Process Progesterone Metabolic Process Ovulation Glutathione Derivative Biosynthetic Process Cellular Response To Toxic Substance Cellular Response To Gonadotropin Stimulus Regulation Of Hormone Biosynthetic Process Mitotic Metaphase Plate Congression Mitotic Chromosome Condensation Positive Regulation Of Steroid Metabolic Process Sister Chromatid Cohesion C21-steroid Hormone Metabolic Process Metaphase Plate Congression Regulation Of Hormone Metabolic Process Cellular Response To Stimulus Androgen Metabolic Process Adrenal Gland Development Response To Gonadotropin Establishment Of Chromosome Localization Chromosome Condensation Hormone Biosynthetic Process Response To Antibiotic Positive Regulation Of Lipid Biosynthetic Process Glutathione Metabolic Process Regulation Of Steroid Biosynthetic Process Hippocampus Development Mitotic Sister Chromatid Segregation
Tagcloud ?			antigen appear approximate bp constitutive contain detoxification downregulates element fragment glutathione gsta2 gstalpha ikaros includes missing named prb promoters repress repression require resemble sufficient sv40 tagr transferase transient weights
Tagcloud (Difference) ?			antigen appear approximate bp constitutive contain detoxification downregulates element fragment glutathione gsta2 gstalpha ikaros includes missing named prb promoters repress repression require resemble sufficient sv40 tagr transferase transient weights
Tagcloud (Intersection) ?