RPAIN and CDCA5

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPAIN	CDCA5
Gene Name		RPA interacting protein	cell division cycle associated 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm PML Body	Chromosome, Centromeric Region Nuclear Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane Cohesin Complex
	Molecular Function	Protein Complex Binding Metal Ion Binding	Chromatin Binding Protein Binding
	Biological Process	DNA-dependent DNA Replication DNA Repair DNA Recombination Protein Import Into Nucleus Response To UV	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Double-strand Break Repair Mitotic Sister Chromatid Cohesion Mitotic Nuclear Division Mitotic Chromosome Condensation Mitotic Metaphase Plate Congression Cell Division Regulation Of Cohesin Localization To Chromatin
Pathways			Establishment of Sister Chromatid Cohesion Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase S Phase Mitotic Metaphase and Anaphase M Phase Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ADH6 CDCA5 CYP17A1 GSTA1	7 interactors: CDK1 IRAK3 KDM1A RPAIN SENP2 TTLL3 XRCC6
Entrez ID		84268	113130
HPRD ID		14615	13016
Ensembl ID		ENSG00000129197	ENSG00000146670
Uniprot IDs		B3KTT3 E9PDG9 Q86UA6	Q96FF9
PDB IDs
Enriched GO Terms of Interacting Partners?		Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Response To Acetate Regulation Of Cohesin Localization To Chromatin Alcohol Metabolic Process Response To Fungicide Phthalate Metabolic Process Positive Regulation Of Steroid Hormone Biosynthetic Process Glucocorticoid Biosynthetic Process Response To Herbicide Response To Methylmercury Dibenzo-p-dioxin Metabolic Process Biphenyl Metabolic Process Positive Regulation Of Hormone Biosynthetic Process Mitotic Sister Chromatid Cohesion Ethanol Oxidation Regulation Of Sister Chromatid Cohesion Androgen Biosynthetic Process Glucocorticoid Metabolic Process Response To Insecticide Leydig Cell Differentiation Cellular Response To Antibiotic Small Molecule Metabolic Process Progesterone Metabolic Process Ovulation Glutathione Derivative Biosynthetic Process Cellular Response To Toxic Substance Cellular Response To Gonadotropin Stimulus Regulation Of Hormone Biosynthetic Process Mitotic Metaphase Plate Congression Mitotic Chromosome Condensation Positive Regulation Of Steroid Metabolic Process Sister Chromatid Cohesion C21-steroid Hormone Metabolic Process Metaphase Plate Congression Regulation Of Hormone Metabolic Process Cellular Response To Stimulus Androgen Metabolic Process Adrenal Gland Development Response To Gonadotropin Establishment Of Chromosome Localization Chromosome Condensation Hormone Biosynthetic Process Response To Antibiotic Positive Regulation Of Lipid Biosynthetic Process Glutathione Metabolic Process Regulation Of Steroid Biosynthetic Process Hippocampus Development Mitotic Sister Chromatid Segregation	Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Protein Binding Negative Regulation Of Intracellular Signal Transduction MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Macrophage Tolerance Induction Regulation Of Primitive Erythrocyte Differentiation Pronuclear Fusion Negative Regulation Of Binding Toll-like Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Embryonic Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Repair Positive Regulation Of Gene Expression Protein Polyglycylation Regulation Of DNA Replication Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Cellular Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cellular Protein Modification Process Activation Of Innate Immune Response Regulation Of Protein Binding Cellular Hyperosmotic Salinity Response Regulation Of Intracellular Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Muscle Cell Development Negative Regulation Of Macrophage Cytokine Production Positive Regulation Of Innate Immune Response Regulation Of Cellular Protein Metabolic Process Protein Desumoylation Cellular Response To DNA Damage Stimulus Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Response To X-ray Positive Regulation Of Immune System Process Immune System Process Negative Regulation Of Chromatin Binding Regulation Of Schwann Cell Differentiation DNA Recombination Regulation Of Protein Metabolic Process Histone H3-K9 Demethylation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K4 Demethylation Establishment Of Integrated Proviral Latency Regulation Of Innate Immune Response Regulation Of Binding Chromosome Organization
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