CAMKK1 and CAMK1D

Number of citations of the paper that reports this interaction (PMID 12935886)
3

Data Source:
HPRD (in vitro)

		CAMKK1	CAMK1D
Gene Name		calcium/calmodulin-dependent protein kinase kinase 1, alpha	calcium/calmodulin-dependent protein kinase ID
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm
	Molecular Function	Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding	Calmodulin-dependent Protein Kinase Activity Calmodulin Binding ATP Binding
	Biological Process	Protein Phosphorylation Synaptic Transmission	Protein Phosphorylation Inflammatory Response Positive Regulation Of Neuron Projection Development Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Phagocytosis Regulation Of Dendrite Development Positive Regulation Of Respiratory Burst Regulation Of Granulocyte Chemotaxis Positive Regulation Of Neutrophil Chemotaxis
Pathways		CREB phosphorylation through the activation of CaMKK Activation of NMDA receptor upon glutamate binding and postsynaptic events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses Post NMDA receptor activation events
Drugs
Diseases
GWAS		Smoking behavior ( 19247474)	Anorexia nervosa ( 23568457) Eating disorders ( 23568457) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443) Type 2 diabetes ( 18372903 20862305)
Protein-Protein Interactions		8 interactors: AKT1 APP CALM1 CAMK1 CAMK1D CAMK4 SGK1 YWHAG	11 interactors: APP ASAH1 BNIP3L CAMKK1 CDC25A CUL3 GMFG NEDD4 NEDD4L POT1 TNFSF13
Entrez ID		84254	57118
HPRD ID		13000	06409
Ensembl ID		ENSG00000004660	ENSG00000183049
Uniprot IDs		F8W9H1 J3KPJ3 Q8N5S9	Q5SQQ7 Q8IU85
PDB IDs			2JC6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transport Regulation Of Intracellular Transport Phosphorylation Regulation Of Neuron Differentiation Positive Regulation Of Intracellular Transport Protein Phosphorylation Regulation Of Catalytic Activity Regulation Of Neurogenesis Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Cell Differentiation Phosphate-containing Compound Metabolic Process Regulation Of Cell Development Regulation Of Cellular Localization Positive Regulation Of Protein Export From Nucleus Establishment Of Localization In Cell Regulation Of Protein Phosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Nervous System Development Positive Regulation Of Monooxygenase Activity Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Phosphorylation Cellular Localization Cellular Response To Fibroblast Growth Factor Stimulus Defense Response Platelet Activation Response To Fibroblast Growth Factor System Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Nitric Oxide Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization Cell Activation Reactive Nitrogen Species Metabolic Process Regulation Of Protein Export From Nucleus Neurotrophin Signaling Pathway Regulation Of Phosphorus Metabolic Process Intracellular Transport Positive Regulation Of Catalytic Activity Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Generation Of Neurons Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Oxidoreductase Activity Nucleocytoplasmic Transport Learning Or Memory Nuclear Transport Regulation Of Protein Localization	Protein Monoubiquitination Negative Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein Polyubiquitination Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Protein Catabolic Process Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cellular Metabolic Process Cellular Protein Modification Process Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Transferase Activity Negative Regulation Of Catalytic Activity Positive Regulation Of Cell Cycle Phase Transition Regulation Of Kinase Activity Regulation Of Potassium Ion Transport Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Regulation Of Sodium Ion Transport Response To Light Stimulus Cellular Macromolecule Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Positive Regulation Of DNA Strand Elongation Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Protein Catabolic Process Protein Metabolic Process Regulation Of Synapse Structure Or Activity Cellular Response To Light Stimulus Negative Regulation Of Ion Transport Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Response To Radiation Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Response To Abiotic Stimulus Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Cell Cycle Cellular Metabolic Process Modification-dependent Protein Catabolic Process Mitochondrial Protein Catabolic Process Telomere Formation Via Telomerase
Tagcloud ?		akt apoptosis br calcium calmodulin er estrogen exact irrespective knockdown largely mb mcf mda moderately neural oncotarget pcp4 pep19 phospho potentially regulates serve sk slightly still thr308 unknown
Tagcloud (Difference) ?		akt apoptosis br calcium calmodulin er estrogen exact irrespective knockdown largely mb mcf mda moderately neural oncotarget pcp4 pep19 phospho potentially regulates serve sk slightly still thr308 unknown
Tagcloud (Intersection) ?