CAMKK1

Gene Name		calcium/calmodulin-dependent protein kinase kinase 1, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding
	Biological Process	Protein Phosphorylation Synaptic Transmission
Pathways		CREB phosphorylation through the activation of CaMKK Activation of NMDA receptor upon glutamate binding and postsynaptic events Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses Post NMDA receptor activation events
Drugs
Diseases
GWAS		Smoking behavior ( 19247474)
Protein-protein Interactions		8 interactors: AKT1 APP CALM1 CAMK1 CAMK1D CAMK4 SGK1 YWHAG
Entrez ID		84254
HPRD ID		13000
Ensembl ID		ENSG00000004660
Uniprot IDs		F8W9H1 J3KPJ3 Q8N5S9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transport Regulation Of Intracellular Transport Phosphorylation Regulation Of Neuron Differentiation Positive Regulation Of Intracellular Transport Protein Phosphorylation Regulation Of Catalytic Activity Regulation Of Neurogenesis Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Cell Differentiation Phosphate-containing Compound Metabolic Process Regulation Of Cell Development Regulation Of Cellular Localization Positive Regulation Of Protein Export From Nucleus Establishment Of Localization In Cell Regulation Of Protein Phosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Nervous System Development Positive Regulation Of Monooxygenase Activity Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Phosphorylation Cellular Localization Cellular Response To Fibroblast Growth Factor Stimulus Defense Response Platelet Activation Response To Fibroblast Growth Factor System Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Nitric Oxide Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization Cell Activation Reactive Nitrogen Species Metabolic Process Regulation Of Protein Export From Nucleus Neurotrophin Signaling Pathway Regulation Of Phosphorus Metabolic Process Intracellular Transport Positive Regulation Of Catalytic Activity Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Generation Of Neurons Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Oxidoreductase Activity Nucleocytoplasmic Transport Learning Or Memory Nuclear Transport Regulation Of Protein Localization
Tagcloud ?		akt apoptosis br calcium calmodulin er estrogen exact irrespective knockdown largely mb mcf mda moderately neural oncotarget pcp4 pep19 phospho potentially regulates serve sk slightly still thr308 unknown