ATRIP and SCG2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ATRIP	SCG2
Gene Name		ATR interacting protein	secretogranin II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Secretory Granule
	Molecular Function	Protein Binding K63-linked Polyubiquitin Binding	Cytokine Activity Chemoattractant Activity
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair	MAPK Cascade Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Positive Regulation Of Endothelial Cell Proliferation Movement Of Cell Or Subcellular Component Inflammatory Response Protein Secretion Intracellular Signal Transduction Endothelial Cell Migration Eosinophil Chemotaxis Positive Chemotaxis Induction Of Positive Chemotaxis Negative Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints
Drugs
Diseases
GWAS			Osteoporosis-related phenotypes ( 20200953) Response to hepatitis C treatment ( 22095909)
Protein-Protein Interactions		21 interactors: ATR BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAM156A FAM208B LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA1 SCG2 SPRY2	3 interactors: ATRIP TUBB4B UBQLN4
Entrez ID		84126	7857
HPRD ID			06762
Ensembl ID		ENSG00000164053	ENSG00000171951
Uniprot IDs		Q8WXE1	P13521
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process DNA Repair Regulation Of Cell Cycle Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Metabolic Process Cell Cycle Checkpoint Cellular Response To DNA Damage Stimulus DNA Replication Organelle Organization Response To Ionizing Radiation Double-strand Break Repair Negative Regulation Of DNA Replication Mitotic Cell Cycle Process Response To Gamma Radiation Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process DNA Recombination Cellular Protein Modification Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Division Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of DNA Metabolic Process Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of DNA Replication DNA Damage Checkpoint Regulation Of Cellular Response To Heat Cell Division Response To Radiation Positive Regulation Of Histone Methylation Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Chromosome Organization Cellular Metabolic Process Establishment Of Spindle Orientation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Histone Methylation Protein Ubiquitination Chromosome Organization
Tagcloud ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg	2kd abcc8 antigenic antigens atp2a2 autoantibodies candidates cd8 copyright destruction encoded glucagon goal infiltrating islet islets min6 nod pancreatic pathogenesis pcsk2 peg3 producing proglucagon protected recognize reserved rights specificities
Tagcloud (Difference) ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg	2kd abcc8 antigenic antigens atp2a2 autoantibodies candidates cd8 copyright destruction encoded glucagon goal infiltrating islet islets min6 nod pancreatic pathogenesis pcsk2 peg3 producing proglucagon protected recognize reserved rights specificities
Tagcloud (Intersection) ?