ATRIP and MX2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ATRIP	MX2
Gene Name		ATR interacting protein	MX dynamin-like GTPase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nuclear Pore Cytoplasm Cytosol
	Molecular Function	Protein Binding K63-linked Polyubiquitin Binding	GTPase Activity GTP Binding
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair	Defense Response Metabolic Process Response To Virus Protein Transport Cytokine-mediated Signaling Pathway Response To Interferon-alpha Regulation Of Nucleocytoplasmic Transport MRNA Transport Defense Response To Virus Regulation Of Cell Cycle Type I Interferon Signaling Pathway
Pathways		G2/M DNA damage checkpoint G2/M Checkpoints Activation of ATR in response to replication stress Cell Cycle Checkpoints	ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling Antiviral mechanism by IFN-stimulated genes
Drugs
Diseases
GWAS			Melanoma ( 21983787)
Protein-Protein Interactions		21 interactors: ATR BRCA1 C1orf94 CCDC28B CDC23 CDC6 CDK16 CEP164 CINP FAM156A FAM208B LNX1 METTL21A MID2 MOS MX2 POLR1C PRKDC RPA1 SCG2 SPRY2	3 interactors: ATRIP EHMT2 PIAS2
Entrez ID		84126	4600
HPRD ID			01001
Ensembl ID		ENSG00000164053	ENSG00000183486
Uniprot IDs		Q8WXE1	P20592
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Cell Cycle Process DNA Repair Regulation Of Cell Cycle Double-strand Break Repair Via Homologous Recombination Recombinational Repair DNA Metabolic Process Cell Cycle Checkpoint Cellular Response To DNA Damage Stimulus DNA Replication Organelle Organization Response To Ionizing Radiation Double-strand Break Repair Negative Regulation Of DNA Replication Mitotic Cell Cycle Process Response To Gamma Radiation Mitotic Cell Cycle Negative Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process DNA Recombination Cellular Protein Modification Process Negative Regulation Of Protein Metabolic Process Regulation Of Cell Division Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Protein Metabolic Process Response To Stress Negative Regulation Of DNA Metabolic Process Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of DNA Replication DNA Damage Checkpoint Regulation Of Cellular Response To Heat Cell Division Response To Radiation Positive Regulation Of Histone Methylation Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Chromosome Organization Cellular Metabolic Process Establishment Of Spindle Orientation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Histone Methylation Protein Ubiquitination Chromosome Organization	Peptidyl-lysine Modification DNA Methylation On Cytosine Within A CG Sequence Histone H3-K27 Methylation Peptidyl-lysine Dimethylation DNA Methylation On Cytosine Negative Regulation Of Androgen Receptor Signaling Pathway Regulation Of Androgen Receptor Signaling Pathway Histone H3-K9 Methylation Synaptonemal Complex Assembly Synaptonemal Complex Organization Protein Sumoylation Histone H3-K9 Modification Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Peptidyl-amino Acid Modification Androgen Receptor Signaling Pathway Cell Cycle Process DNA Metabolic Process Synapsis Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Homologous Chromosome Segregation Nucleobase-containing Compound Metabolic Process DNA Methylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Cell Cycle Cellular Nitrogen Compound Metabolic Process
Tagcloud ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg
Tagcloud (Difference) ?		biochemically canonical checkpoint checkpoints concert constitute damage damaged enlargement ercc1 excision exo1 exonuclease gap integrity mimetic minimum nucleotide repair rpa steps stranded tfiih topbp1 xpa xpc xpf xpg
Tagcloud (Intersection) ?