FXR1 and CYFIP2

Number of citations of the paper that reports this interaction (PMID 11438699)
59

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		FXR1	CYFIP2
Gene Name		fragile X mental retardation, autosomal homolog 1	cytoplasmic FMR1 interacting protein 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Polysome Membrane Costamere	Cytoplasm Cytosol Membrane Cell Junction Neuron Projection Synapse Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	G-quadruplex RNA Binding RNA Binding MRNA Binding MRNA 3'-UTR Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation	Apoptotic Process Single Organismal Cell-cell Adhesion Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Positive Regulation Of Proteolysis Vascular Endothelial Growth Factor Receptor Signaling Pathway Activation Of Cysteine-type Endopeptidase Activity
Pathways			Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS		Schizophrenia ( 19571811)
Protein-Protein Interactions		11 interactors: C14orf1 CRMP1 CSNK2A1 CYFIP2 FMR1 FXR2 GBP2 KIAA1377 LRIF1 LUC7L2 PRSS23	20 interactors: ABI1 ABI3 APBB1 BIRC3 BRK1 DNMBP FMR1 FXR1 FXR2 GAS7 NCK1 NCKAP1 PLG PRPF40A SMAD4 TCERG1 WASF1 WASF2 YWHAG ZC3H12A
Entrez ID		8087	26999
HPRD ID		02892	07556
Ensembl ID		ENSG00000114416	ENSG00000055163
Uniprot IDs		B4DXZ6 E9PFF5 P51114	E7EVJ5 E7EW33 F5H583 Q96F07
PDB IDs		2CPQ 3KUF 3O8V
Enriched GO Terms of Interacting Partners?			Rac Protein Signal Transduction Movement Of Cell Or Subcellular Component Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Lamellipodium Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Lamellipodium Assembly Negative Regulation Of Protein Metabolic Process Actin Cytoskeleton Organization Positive Regulation Of Lamellipodium Organization Actin Filament-based Process Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Cellular Component Organization Regulation Of Actin Nucleation Regulation Of Lamellipodium Assembly Regulation Of Cellular Process Immune Response-regulating Signaling Pathway Cytoskeleton Organization Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Locomotion Cell Motility Lamellipodium Morphogenesis Negative Regulation Of Biosynthetic Process Lamellipodium Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Multicellular Organismal Development Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Anatomical Structure Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cytoskeleton Organization System Development Cell Projection Organization Regulation Of Protein Metabolic Process Posttranscriptional Regulation Of Gene Expression Ras Protein Signal Transduction Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Somitogenesis Cell Migration Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Negative Regulation Of Translation
Tagcloud ?		address adhesion arm comprised coprecipitated cytoplasm cytoplasmic desmoplakin desmosomes destabilized g3bp gain mrnas outside pabpc1 particles pkp1 pkp2 pkp3 plakophilins posttranscriptional regulators repeat ribonucleoprotein rnase serve stabilized unaffected upf1	als amyotrophic beacons biomarkers creating discovered etiology fals familial fatal g93a hmsc inherited leukocyte msod1 ones path pathogenetic pave rbbp9 sals secretory share signature slpi sod1 spatiotemporal sporadic tar
Tagcloud (Difference) ?		address adhesion arm comprised coprecipitated cytoplasm cytoplasmic desmoplakin desmosomes destabilized g3bp gain mrnas outside pabpc1 particles pkp1 pkp2 pkp3 plakophilins posttranscriptional regulators repeat ribonucleoprotein rnase serve stabilized unaffected upf1	als amyotrophic beacons biomarkers creating discovered etiology fals familial fatal g93a hmsc inherited leukocyte msod1 ones path pathogenetic pave rbbp9 sals secretory share signature slpi sod1 spatiotemporal sporadic tar
Tagcloud (Intersection) ?