COASY and RPS6KB2

Number of citations of the paper that reports this interaction (PMID 15589845)
2

Data Source:
HPRD (in vivo)

		COASY	RPS6KB2
Gene Name		CoA synthase	ribosomal protein S6 kinase, 70kDa, polypeptide 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm
	Molecular Function	Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Ribosomal Protein S6 Kinase Activity ATP Binding Peptide Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process Pantothenate Metabolic Process Phosphorylation Small Molecule Metabolic Process	Translation Protein Phosphorylation Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Protein Kinase B Signaling Innate Immune Response Positive Regulation Of Translational Initiation Neurotrophin TRK Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism	Signaling by the B Cell Receptor (BCR) Signaling by FGFR in disease PIP3 activates AKT signaling Signaling by EGFRvIII in Cancer Signaling by SCF-KIT DAP12 signaling Downstream signaling events of B Cell Receptor (BCR) PI3K/AKT activation PI-3K cascade PI3K events in ERBB2 signaling Downstream signaling of activated FGFR Innate Immune System Signaling by PDGF DAP12 interactions Signalling by NGF GAB1 signalosome Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by ERBB4 Constitutive PI3K/AKT Signaling in Cancer Role of LAT2/NTAL/LAB on calcium mobilization PI3K events in ERBB4 signaling Signaling by FGFR Signaling by ERBB2 Signaling by EGFR AKT phosphorylates targets in the nucleus Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer PI3K/AKT Signaling in Cancer Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP CNTROB KIAA1958 KRT20 RPS6KB1 RPS6KB2	20 interactors: ATP5A1 BRAF BTK COASY CSNK2B EEF2K EP300 FBXO25 IKBKG KAT2B LYN MAPK8IP2 MTOR NEDD4L PDPK1 PRKCE RPS6 SRC SRPK1 SYK
Entrez ID		80347	6199
HPRD ID		13080	10203
Ensembl ID		ENSG00000068120	ENSG00000175634
Uniprot IDs		Q13057	Q9UBS0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Translational Initiation Regulation Of Translation Protein Kinase B Signaling Posttranscriptional Regulation Of Gene Expression Regulation Of Translational Initiation Positive Regulation Of Translation Positive Regulation Of Mitotic Cell Cycle Phosphatidylinositol-mediated Signaling Synaptic Growth At Neuromuscular Junction Positive Regulation Of Skeletal Muscle Tissue Growth Collateral Sprouting In Absence Of Injury Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Skeletal Muscle Atrophy Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Striated Muscle Atrophy Response To Leucine Learning Or Memory Positive Regulation Of Protein Metabolic Process Axon Choice Point Recognition Muscle Atrophy Positive Regulation Of Cell Cycle Regulation Of Developmental Growth Cognition Mitotic Cytokinetic Process Protein Phosphorylation Skeletal Muscle Adaptation Neuron Remodeling Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Mitotic Cell Cycle Centrosome Separation Centriole Replication Single-organism Behavior Intermediate Filament Organization Cellular Copper Ion Homeostasis Phosphorylation TOR Signaling Copper Ion Homeostasis Suckling Behavior Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Regulation Of Protein Phosphorylation Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Fc Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Phosphate-containing Compound Metabolic Process Intracellular Signal Transduction Regulation Of Kinase Activity Viral Process Regulation Of Phosphorus Metabolic Process Innate Immune Response Protein Autophosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Response To Organic Substance Cell Surface Receptor Signaling Pathway Cellular Protein Modification Process Response To Hormone Immune Response Protein Phosphorylation Response To Peptide Hormone Defense Response Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Response To Insulin Response To Peptide Cellular Protein Metabolic Process Cellular Response To Organic Substance Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Response To Organonitrogen Compound Cellular Response To Hormone Stimulus Signaling Positive Regulation Of Cell Adhesion Positive Regulation Of Protein Metabolic Process Cellular Response To Insulin Stimulus Cell Communication Positive Regulation Of Protein Modification Process Immune System Process Fc-epsilon Receptor Signaling Pathway Peptidyl-amino Acid Modification Peptidyl-tyrosine Autophosphorylation Cell Activation Cellular Metabolic Process
Tagcloud ?		aceruloplasminemia atp13a2 autophagosome avenues c19orf12 c2orf37 ceruloplasmin comprehension connection description eventually fa2h faster ftl hope infer iron let metabolism nbia neurodegenerative neuroferritinopathy nucleolar pank2 pave perturbation pla2g6 underlining wdr45	administrated arylnaphthalide atg12 atg5 autophagic bafilomycin beclin bnip3 chloroquine inc ja justicia justicidin lc3 lignan methyladenine mrfp p62 p70s6k pdk1 periodicals physiol procumbens ptflc3 puncta shrna sqstm1 vad wiley
Tagcloud (Difference) ?		aceruloplasminemia atp13a2 autophagosome avenues c19orf12 c2orf37 ceruloplasmin comprehension connection description eventually fa2h faster ftl hope infer iron let metabolism nbia neurodegenerative neuroferritinopathy nucleolar pank2 pave perturbation pla2g6 underlining wdr45	administrated arylnaphthalide atg12 atg5 autophagic bafilomycin beclin bnip3 chloroquine inc ja justicia justicidin lc3 lignan methyladenine mrfp p62 p70s6k pdk1 periodicals physiol procumbens ptflc3 puncta shrna sqstm1 vad wiley
Tagcloud (Intersection) ?