COASY and KIAA1958

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		COASY	KIAA1958
Gene Name		CoA synthase	KIAA1958
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process Pantothenate Metabolic Process Phosphorylation Small Molecule Metabolic Process
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: APP CNTROB KIAA1958 KRT20 RPS6KB1 RPS6KB2	11 interactors: AQP1 CEP19 COASY FAM124B GABARAPL2 LMO4 MCRS1 RWDD2B SOCS3 STAC TCEA2
Entrez ID		80347	158405
HPRD ID		13080	11173
Ensembl ID		ENSG00000068120	ENSG00000165185
Uniprot IDs		Q13057	B7ZKW6 Q8N8K9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Translational Initiation Regulation Of Translation Protein Kinase B Signaling Posttranscriptional Regulation Of Gene Expression Regulation Of Translational Initiation Positive Regulation Of Translation Positive Regulation Of Mitotic Cell Cycle Phosphatidylinositol-mediated Signaling Synaptic Growth At Neuromuscular Junction Positive Regulation Of Skeletal Muscle Tissue Growth Collateral Sprouting In Absence Of Injury Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Skeletal Muscle Atrophy Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Striated Muscle Atrophy Response To Leucine Learning Or Memory Positive Regulation Of Protein Metabolic Process Axon Choice Point Recognition Muscle Atrophy Positive Regulation Of Cell Cycle Regulation Of Developmental Growth Cognition Mitotic Cytokinetic Process Protein Phosphorylation Skeletal Muscle Adaptation Neuron Remodeling Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Mitotic Cell Cycle Centrosome Separation Centriole Replication Single-organism Behavior Intermediate Filament Organization Cellular Copper Ion Homeostasis Phosphorylation TOR Signaling Copper Ion Homeostasis Suckling Behavior Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Corticotropin Secretion Carbon Dioxide Transmembrane Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cellular Response To Mercury Ion Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Metanephric Proximal Tubule Development Spongiotrophoblast Differentiation Cellular Response To Stress Purine Nucleotide Biosynthetic Process Positive Regulation Of Saliva Secretion Renal Water Absorption Carbon Dioxide Transport Epithelial Fluid Transport Ribose Phosphate Biosynthetic Process Renal Water Transport Cellular Response To Copper Ion Regulation Of Saliva Secretion Pancreatic Juice Secretion Proximal Tubule Development Negative Regulation Of Cellular Protein Metabolic Process Metanephric Loop Of Henle Development Cerebrospinal Fluid Secretion Cardiovascular System Development Cellular Hyperosmotic Response Hyperosmotic Salinity Response Negative Regulation Of Protein Metabolic Process Metanephric Glomerulus Vasculature Development Glycerol Transport Branching Involved In Labyrinthine Layer Morphogenesis Cellular Response To Salt Stress Pantothenate Metabolic Process Positive Regulation Of Digestive System Process Response To Stress Renal Absorption Loop Of Henle Development Lipid Digestion Histone H4-K5 Acetylation Histone H4-K8 Acetylation Polyol Transport Cellular Response To Nitric Oxide Ribonucleotide Metabolic Process Transepithelial Transport Cellular Water Homeostasis Nucleotide Biosynthetic Process
Tagcloud ?		aceruloplasminemia atp13a2 autophagosome avenues c19orf12 c2orf37 ceruloplasmin comprehension connection description eventually fa2h faster ftl hope infer iron let metabolism nbia neurodegenerative neuroferritinopathy nucleolar pank2 pave perturbation pla2g6 underlining wdr45
Tagcloud (Difference) ?		aceruloplasminemia atp13a2 autophagosome avenues c19orf12 c2orf37 ceruloplasmin comprehension connection description eventually fa2h faster ftl hope infer iron let metabolism nbia neurodegenerative neuroferritinopathy nucleolar pank2 pave perturbation pla2g6 underlining wdr45
Tagcloud (Intersection) ?