KDM8 and PCYT2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KDM8	PCYT2
Gene Name		lysine (K)-specific demethylase 8	phosphate cytidylyltransferase 2, ethanolamine
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Cellular_component Endoplasmic Reticulum Membrane
	Molecular Function	Chromatin Binding Metal Ion Binding Histone Demethylase Activity (H3-K36 Specific)	Ethanolamine-phosphate Cytidylyltransferase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process Histone H3-K36 Demethylation	Phospholipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phospholipid Biosynthetic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process
Pathways			Metabolism of lipids and lipoproteins Synthesis of PE Phospholipid metabolism Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: PCYT2	6 interactors: ADAMTS10 CRIP2 DNMT3B GDF9 KDM8 SETDB1
Entrez ID		79831	5833
HPRD ID		07836	04059
Ensembl ID		ENSG00000155666
Uniprot IDs		Q8N371	B3KSC8 B7Z4W6 B7ZAS0 Q99447
PDB IDs		3UYJ 4AAP 4GAZ 4GJY 4GJZ	3ELB
Enriched GO Terms of Interacting Partners?		Phosphatidylethanolamine Biosynthetic Process Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process	Chromatin Modification Oocyte Growth Chromatin Organization S-adenosylmethioninamine Metabolic Process DNA Methylation On Cytosine Within A CG Sequence Regulation Of Progesterone Secretion C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Chromosome Organization Histone H3-K36 Demethylation Methylation-dependent Chromatin Silencing Developmental Growth Histone H3-K9 Trimethylation Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Regulation Of Female Gonad Development Histone Modification Positive Regulation Of Histone H3-K4 Methylation Methylation Negative Regulation Of Histone Methylation Protein Complex Localization Histone H3-K9 Methylation Inner Cell Mass Cell Proliferation
Tagcloud ?		asparaginyl barrel cleft demethylases demethylate dimethylated embryological fih h3k36 h3k36me2 histidinyl hydroxylase illustrates jmjc jmjd5 jmjd6 jumonji kdms lysyl methyllysines nog og opens oxalylglycine oxoglutarate rhythm shallow shares tyw5
Tagcloud (Difference) ?		asparaginyl barrel cleft demethylases demethylate dimethylated embryological fih h3k36 h3k36me2 histidinyl hydroxylase illustrates jmjc jmjd5 jmjd6 jumonji kdms lysyl methyllysines nog og opens oxalylglycine oxoglutarate rhythm shallow shares tyw5
Tagcloud (Intersection) ?