PCYT2 and KDM8

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PCYT2	KDM8
Gene Name		phosphate cytidylyltransferase 2, ethanolamine	lysine (K)-specific demethylase 8
Image
Gene Ontology Annotations	Cellular Component	Cellular_component Endoplasmic Reticulum Membrane	Nucleus
	Molecular Function	Ethanolamine-phosphate Cytidylyltransferase Activity	Chromatin Binding Metal Ion Binding Histone Demethylase Activity (H3-K36 Specific)
	Biological Process	Phospholipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Phospholipid Biosynthetic Process Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process	G2/M Transition Of Mitotic Cell Cycle Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process Histone H3-K36 Demethylation
Pathways		Metabolism of lipids and lipoproteins Synthesis of PE Phospholipid metabolism Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ADAMTS10 CRIP2 DNMT3B GDF9 KDM8 SETDB1	1 interactors: PCYT2
Entrez ID		5833	79831
HPRD ID		04059	07836
Ensembl ID			ENSG00000155666
Uniprot IDs		B3KSC8 B7Z4W6 B7ZAS0 Q99447	Q8N371
PDB IDs		3ELB	3UYJ 4AAP 4GAZ 4GJY 4GJZ
Enriched GO Terms of Interacting Partners?		Chromatin Modification Oocyte Growth Chromatin Organization S-adenosylmethioninamine Metabolic Process DNA Methylation On Cytosine Within A CG Sequence Regulation Of Progesterone Secretion C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Chromosome Organization Histone H3-K36 Demethylation Methylation-dependent Chromatin Silencing Developmental Growth Histone H3-K9 Trimethylation Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Regulation Of Female Gonad Development Histone Modification Positive Regulation Of Histone H3-K4 Methylation Methylation Negative Regulation Of Histone Methylation Protein Complex Localization Histone H3-K9 Methylation Inner Cell Mass Cell Proliferation	Phosphatidylethanolamine Biosynthetic Process Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Glycerophospholipid Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process
Tagcloud ?			asparaginyl barrel cleft demethylases demethylate dimethylated embryological fih h3k36 h3k36me2 histidinyl hydroxylase illustrates jmjc jmjd5 jmjd6 jumonji kdms lysyl methyllysines nog og opens oxalylglycine oxoglutarate rhythm shallow shares tyw5
Tagcloud (Difference) ?			asparaginyl barrel cleft demethylases demethylate dimethylated embryological fih h3k36 h3k36me2 histidinyl hydroxylase illustrates jmjc jmjd5 jmjd6 jumonji kdms lysyl methyllysines nog og opens oxalylglycine oxoglutarate rhythm shallow shares tyw5
Tagcloud (Intersection) ?