LAPTM5 and UBAC1

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		LAPTM5	UBAC1
Gene Name		lysosomal protein transmembrane 5	UBA domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Integral Component Of Plasma Membrane	Cytoplasm Golgi Apparatus Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function		Protein Binding
	Biological Process	Transport	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		25 interactors: ANKRD13A DCUN1D1 DISP1 EPN1 EPN2 EPN3 EPS15 HERC1 HEY1 HEYL HUWE1 ITCH KRT7 LDLRAD1 NEDD4 NEDD4L RNF168 SMURF2 TNFAIP3 TOM1L2 UBA52 UBAC1 UBC USP13 WWP1	14 interactors: AIRE APP CDKN1B CPSF6 CSNK2A1 DAZAP2 HTT LAPTM5 NEDD4L RNF11 RNF123 TRIM2 TRIM39 ZDHHC17
Entrez ID		7805	10422
HPRD ID		03280	12170
Ensembl ID		ENSG00000162511	ENSG00000130560
Uniprot IDs		Q13571 Q5TBB8	Q9BSL1
PDB IDs			2DAI
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Notch Signaling Pathway Protein Catabolic Process Negative Regulation Of Signal Transduction Cellular Macromolecule Catabolic Process Negative Regulation Of Signaling Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Proteolysis Positive Regulation Of Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Viral Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Cellular Protein Modification Process Viral Life Cycle Regulation Of ERBB Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Signal Transduction Negative Regulation Of Biosynthetic Process Catabolic Process Cellular Response To Stimulus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Type I Interferon Production Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein K63-linked Ubiquitination Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signal Transduction	Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Protein Catabolic Process Cellular Protein Modification Process Apoptotic Process MRNA Polyadenylation Programmed Cell Death Positive Regulation Of Cation Channel Activity Cell Death Death RNA Polyadenylation Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Growth Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Proteolysis Axon Cargo Transport Mating Positive Regulation Of Transporter Activity Positive Regulation Of Cell Cycle Neuron Apoptotic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Visual Learning Protein Metabolic Process Regulation Of Protein Metabolic Process Neural Plate Formation Visual Behavior Neuron Death Cellular Protein Metabolic Process Response To Metal Ion Regulation Of Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Ion Transmembrane Transport Negative Regulation Of Cellular Protein Catabolic Process Regulation Of Cation Channel Activity Negative Regulation Of Proteolysis Metal Ion Transport MRNA 3'-end Processing Negative Regulation Of Protein Processing Regulation Of Cell Death Associative Learning Negative Regulation Of Protein Metabolic Process Regulation Of Endopeptidase Activity Synaptic Growth At Neuromuscular Junction Serotonin Uptake Positive Regulation Of Caveolin-mediated Endocytosis Lactate Biosynthetic Process From Pyruvate Regulation Of Protein Processing Regulation Of Cell Cycle
Tagcloud ?		bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification
Tagcloud (Difference) ?		bioinformatics cd53 coeruleus ctss cx3cr1 degs downloaded encyclopedia enriched excision genomes glycan gse34516 hub idiopathic igsf6 ipd kyoto mismatch mortem omnibus ontology paired ppi ptprc slc5a7 spliceosome splicing transesterification
Tagcloud (Intersection) ?