TUBB2A and TPT1

Number of citations of the paper that reports this interaction (PMID 15870695)
34

Data Source:
BioGRID (unspecified method)

		TUBB2A	TPT1
Gene Name		tubulin, beta 2A class IIa	tumor protein, translationally-controlled 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Vesicle Extracellular Vesicular Exosome	Extracellular Space Nucleus Cytoplasm Multivesicular Body Tubulin Complex Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton GTP Binding	Calcium Ion Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Folding Microtubule-based Process Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Transmembrane Transport	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Orphan transporters Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ACD ARL15 CHGB DISC1 HDAC6 HGS HMMR LAMA4 PAFAH1B3 POT1 PSMD11 PTPRS RABAC1 RIC8A RPA2 RPLP1 SAT1 SDC3 SERPINB9 TERF1 TK1 TNIK TPT1 UPF2	25 interactors: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1D FANCA IKBKG LIG4 MCL1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A
Entrez ID		7280	7178
HPRD ID			15979
Ensembl ID		ENSG00000137267	ENSG00000133112
Uniprot IDs		Q13885	P13693 Q8TBK7
PDB IDs			1YZ1 2HR9 3EBM
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Assembly Regulation Of DNA Biosynthetic Process Telomere Capping Negative Regulation Of DNA Replication Catabolic Process Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Cellular Protein Localization Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly RNA-dependent DNA Replication Regulation Of DNA Replication Negative Regulation Of DNA Biosynthetic Process Response To Stimulus Developmental Process Regulation Of Proteolysis Negative Regulation Of Mitotic Cell Cycle Phase Transition Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Protein Catabolic Process Mitotic Cell Cycle Checkpoint Glycosaminoglycan Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Chromosome Organization Cellular Macromolecule Catabolic Process Cellular Localization Pathogenesis Cell-cell Adhesion Involved In Gastrulation Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Fetal Process Involved In Parturition Hsp90 Deacetylation Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Homeostatic Process Protein Localization Intracellular Protein Transport Regulation Of Cell Cycle Phase Transition	Regulation Of Response To DNA Damage Stimulus Cell Communication By Electrical Coupling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Stimulus Cellular Response To DNA Damage Stimulus Response To Organic Cyclic Compound Response To Glycoside Apoptotic Process Regulation Of The Force Of Heart Contraction Response To Radiation Programmed Cell Death Positive Regulation Of Mitotic Cell Cycle Cell Death Death Response To Steroid Hormone Response To Abiotic Stimulus Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Response To Stress Sodium Ion Export From Cell Response To Lipid Regulation Of Signaling Cardiac Muscle Contraction Response To Stimulus Regulation Of Heart Contraction Neuron Apoptotic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Sodium Ion Export Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cellular Potassium Ion Homeostasis Cellular Response To Steroid Hormone Stimulus Neuron Death Cell Cycle Heart Contraction Cellular Response To Organic Cyclic Compound Intracellular Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitotic Cell Cycle Regulation Of Cellular Localization Cellular Response To Lipid Regulation Of Cardiac Muscle Contraction Regulation Of Neurogenesis Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Apoptotic Process Muscle Contraction Regulation Of Cellular Process Negative Regulation Of Mitotic Cell Cycle Cellular Localization
Tagcloud ?			2o2 activating adds antioxidant avenue challenge chemoresistance complexity contain continuously correlation differentially direct diverse element existed fact lung maintains minimize mutated network open p53 promote responsive reversion stability upregulates
Tagcloud (Difference) ?			2o2 activating adds antioxidant avenue challenge chemoresistance complexity contain continuously correlation differentially direct diverse element existed fact lung maintains minimize mutated network open p53 promote responsive reversion stability upregulates
Tagcloud (Intersection) ?