TUBB2A and PAFAH1B3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)

		TUBB2A	PAFAH1B3
Gene Name		tubulin, beta 2A class IIa	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Vesicle Extracellular Vesicular Exosome	Cytoplasm Cytosol Membrane Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton GTP Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Protein Folding Microtubule-based Process Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Transmembrane Transport	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process
Pathways		Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Orphan transporters Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: ACD ARL15 CHGB DISC1 HDAC6 HGS HMMR LAMA4 PAFAH1B3 POT1 PSMD11 PTPRS RABAC1 RIC8A RPA2 RPLP1 SAT1 SDC3 SERPINB9 TERF1 TK1 TNIK TPT1 UPF2	33 interactors: BRD7 C14orf1 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 PAFAH1B1 PAFAH1B2 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1
Entrez ID		7280	5050
HPRD ID			04354
Ensembl ID		ENSG00000137267	ENSG00000079462
Uniprot IDs		Q13885	Q15102
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Assembly Regulation Of DNA Biosynthetic Process Telomere Capping Negative Regulation Of DNA Replication Catabolic Process Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Cellular Protein Localization Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly RNA-dependent DNA Replication Regulation Of DNA Replication Negative Regulation Of DNA Biosynthetic Process Response To Stimulus Developmental Process Regulation Of Proteolysis Negative Regulation Of Mitotic Cell Cycle Phase Transition Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Protein Catabolic Process Mitotic Cell Cycle Checkpoint Glycosaminoglycan Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Catalytic Activity Regulation Of Chromosome Organization Cellular Macromolecule Catabolic Process Cellular Localization Pathogenesis Cell-cell Adhesion Involved In Gastrulation Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Fetal Process Involved In Parturition Hsp90 Deacetylation Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Homeostatic Process Protein Localization Intracellular Protein Transport Regulation Of Cell Cycle Phase Transition	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance RNA Biosynthetic Process Regulation Of Chromosome Organization Telomere Maintenance Negative Regulation Of Gene Expression Cell Division Negative Regulation Of DNA Metabolic Process RNA Metabolic Process Cell Separation After Cytokinesis Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomere Maintenance Negative Regulation Of Transcription, DNA-templated RNA-dependent DNA Replication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Response To X-ray Cellular Macromolecule Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Cell Cycle Phase Transition Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Fibroblast Proliferation Biosynthetic Process Macromolecule Biosynthetic Process Response To Salt Stress Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Stem Cell Division Chromosome Organization Mitotic Cell Cycle Process Negative Regulation Of Clathrin-mediated Endocytosis Peptidyl-cysteine S-trans-nitrosylation Negative Regulation Of DNA Recombination At Telomere Regulation Of Mitotic Cell Cycle Negative Regulation Of DNA Replication Gene Expression Mitotic Cell Cycle Neuron Apoptotic Process Cellular Response To Ionizing Radiation Negative Regulation Of Transcription From RNA Polymerase II Promoter 'de Novo' Posttranslational Protein Folding Metabolic Process
Tagcloud ?			abpp acetylhydrolase acyl aided campaign carbamate carbamoylation cherry endeavored fluopol hits house hts hydrolase hydrolases medchem ml256 mudpit oxidatively phospholipids picked pla2g7 scaffold sid tunable
Tagcloud (Difference) ?			abpp acetylhydrolase acyl aided campaign carbamate carbamoylation cherry endeavored fluopol hits house hts hydrolase hydrolases medchem ml256 mudpit oxidatively phospholipids picked pla2g7 scaffold sid tunable
Tagcloud (Intersection) ?