TNXB and VEGFB

Number of citations of the paper that reports this interaction (PMID 11122379)
7

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		TNXB	VEGFB
Gene Name		tenascin XB	vascular endothelial growth factor B
Image
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Fibrillar Collagen Trimer Extracellular Space Intracellular Extracellular Matrix Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Membrane Platelet Alpha Granule Lumen
	Molecular Function	Integrin Binding Collagen Binding Heparin Binding	Protein Binding Growth Factor Activity Heparin Binding Chemoattractant Activity Protein Homodimerization Activity Vascular Endothelial Growth Factor Receptor 1 Binding Protein Heterodimerization Activity
	Biological Process	Fatty Acid Metabolic Process Triglyceride Metabolic Process Cell Adhesion Cell-matrix Adhesion Single Organismal Cell-cell Adhesion Actin Cytoskeleton Organization Collagen Fibril Organization Collagen Metabolic Process Extracellular Fibril Organization Regulation Of JUN Kinase Activity Elastic Fiber Assembly	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Platelet Degranulation Protein O-linked Glycosylation Blood Coagulation Negative Regulation Of Gene Expression Platelet Activation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Vascular Wound Healing Response To Drug Negative Regulation Of Apoptotic Process Positive Regulation Of Vascular Permeability Negative Regulation Of Neuron Apoptotic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Chemotaxis Induction Of Positive Chemotaxis Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling Cardiac Muscle Contraction Positive Regulation Of Mast Cell Chemotaxis Coronary Vasculature Development Positive Regulation Of ERK1 And ERK2 Cascade
Pathways		ECM proteoglycans	VEGF binds to VEGFR leading to receptor dimerization VEGF ligand-receptor interactions Signaling by VEGF Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS		Age-related macular degeneration ( 22694956) HIV-1 control ( 20041166) Phospholipid levels (plasma) ( 21829377) Prostate cancer ( 23535732) Systemic lupus erythematosus ( 21408207)
Protein-Protein Interactions		3 interactors: BANP VEGFA VEGFB	6 interactors: ADRB2 FLT1 KLHL12 NRP1 TNXB VEGFA
Entrez ID		7148	7423
HPRD ID		02993	03237
Ensembl ID		ENSG00000168477
Uniprot IDs		O95680 O95681 P22105 Q6IPK3 Q9Y464	P49765 Q7LAP4
PDB IDs		2CUH 2CUI 2CUM	2C7W 2VWE 2XAC
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mast Cell Chemotaxis Coronary Vasculature Development Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Induction Of Positive Chemotaxis Positive Chemotaxis Positive Regulation Of Positive Chemotaxis Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Leukocyte Chemotaxis Platelet Degranulation Positive Regulation Of Protein Kinase B Signaling Regulation Of Endothelial Cell Proliferation Positive Regulation Of Leukocyte Migration Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Cell Division Positive Regulation Of Behavior Regulation Of Protein Kinase B Signaling Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Chemotaxis Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Protein Kinase D Signaling Basophil Chemotaxis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Regulation Of ERK1 And ERK2 Cascade Platelet Activation Negative Regulation Of Neuron Death Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Retinal Ganglion Cell Axon Guidance Coronary Vein Morphogenesis Primitive Erythrocyte Differentiation VEGF-activated Neuropilin Signaling Pathway Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Vascular Wound Healing Regulation Of Angiogenesis Regulation Of Neuron Apoptotic Process Regulation Of Cell Division Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Histone Deacetylase Activity Regulation Of Epithelial Cell Proliferation Regulation Of Neuron Death Positive Regulation Of Lymphangiogenesis Regulation Of Retinal Ganglion Cell Axon Guidance	Vascular Endothelial Growth Factor Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Retinal Ganglion Cell Axon Guidance VEGF-activated Neuropilin Signaling Pathway Regulation Of MAPK Cascade Patterning Of Blood Vessels Sprouting Angiogenesis Regulation Of Retinal Ganglion Cell Axon Guidance Coronary Artery Morphogenesis Regulation Of Protein Phosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Endothelial Cell Chemotaxis Positive Regulation Of Axon Extension Involved In Axon Guidance Positive Regulation Of MAPK Cascade Coronary Vasculature Morphogenesis Regulation Of Signal Transduction Regulation Of Phosphorylation Commissural Neuron Axon Guidance Regulation Of Signaling Coronary Vasculature Development Regulation Of Phosphorus Metabolic Process Cell Chemotaxis Regulation Of Axon Extension Involved In Axon Guidance Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Migration Involved In Sprouting Angiogenesis Branching Morphogenesis Of An Epithelial Tube Positive Regulation Of Protein Phosphorylation Regulation Of Intracellular Signal Transduction Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Chemotaxis Positive Regulation Of Intracellular Signal Transduction Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Blood Vessel Endothelial Cell Migration Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Developmental Growth Regulation Of MAP Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of Axon Extension Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Angiogenesis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility
Tagcloud ?			11q13 250bp 4kb caenorhabditis centromeric characterisation designated dnaj elegans encode greatest homolog hspf2 interrupted introns keratinocytes lies mcg18 message name neoplasia ovary searches sequenced shares similarity spanning undefined vrf
Tagcloud (Difference) ?			11q13 250bp 4kb caenorhabditis centromeric characterisation designated dnaj elegans encode greatest homolog hspf2 interrupted introns keratinocytes lies mcg18 message name neoplasia ovary searches sequenced shares similarity spanning undefined vrf
Tagcloud (Intersection) ?