TNXB

Gene Name		tenascin XB
Image
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Fibrillar Collagen Trimer Extracellular Space Intracellular Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Integrin Binding Collagen Binding Heparin Binding
	Biological Process	Fatty Acid Metabolic Process Triglyceride Metabolic Process Cell Adhesion Cell-matrix Adhesion Single Organismal Cell-cell Adhesion Actin Cytoskeleton Organization Collagen Fibril Organization Collagen Metabolic Process Extracellular Fibril Organization Regulation Of JUN Kinase Activity Elastic Fiber Assembly
Pathways		ECM proteoglycans
Drugs
Diseases
GWAS		Age-related macular degeneration ( 22694956) HIV-1 control ( 20041166) Phospholipid levels (plasma) ( 21829377) Prostate cancer ( 23535732) Systemic lupus erythematosus ( 21408207)
Protein-protein Interactions		3 interactors: BANP VEGFA VEGFB
Entrez ID		7148
HPRD ID		02993
Ensembl ID		ENSG00000168477
Uniprot IDs		O95680 O95681 P22105 Q6IPK3 Q9Y464
PDB IDs		2CUH 2CUI 2CUM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mast Cell Chemotaxis Coronary Vasculature Development Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Induction Of Positive Chemotaxis Positive Chemotaxis Positive Regulation Of Positive Chemotaxis Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Proliferation Positive Regulation Of Leukocyte Chemotaxis Platelet Degranulation Positive Regulation Of Protein Kinase B Signaling Regulation Of Endothelial Cell Proliferation Positive Regulation Of Leukocyte Migration Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Cell Division Positive Regulation Of Behavior Regulation Of Protein Kinase B Signaling Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Chemotaxis Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Protein Kinase D Signaling Basophil Chemotaxis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Behavior Regulation Of ERK1 And ERK2 Cascade Platelet Activation Negative Regulation Of Neuron Death Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Retinal Ganglion Cell Axon Guidance Coronary Vein Morphogenesis Primitive Erythrocyte Differentiation VEGF-activated Neuropilin Signaling Pathway Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Vascular Wound Healing Regulation Of Angiogenesis Regulation Of Neuron Apoptotic Process Regulation Of Cell Division Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Histone Deacetylase Activity Regulation Of Epithelial Cell Proliferation Regulation Of Neuron Death Positive Regulation Of Lymphangiogenesis Regulation Of Retinal Ganglion Cell Axon Guidance
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