TEAD3 and MYH7

Number of citations of the paper that reports this interaction (PMID 12861002)
21

Data Source:
HPRD (in vitro)

		TEAD3	MYH7
Gene Name		TEA domain family member 3	myosin, heavy chain 7, cardiac muscle, beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex	Stress Fiber Nucleoplasm Cytoplasm Muscle Myosin Complex Focal Adhesion Myosin Complex Sarcomere Z Disc Myosin Filament
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Microfilament Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding ATPase Activity Actin-dependent ATPase Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Gene Expression Hippo Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Stem Cell Maintenance	Regulation Of The Force Of Heart Contraction Regulation Of Heart Rate Muscle Contraction Striated Muscle Contraction Adult Heart Development Muscle Filament Sliding Ventricular Cardiac Muscle Tissue Morphogenesis
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS			Resting heart rate ( 20639392)
Protein-Protein Interactions		13 interactors: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 WWTR1 YAP1	4 interactors: KXD1 TEAD1 TEAD3 TEAD4
Entrez ID		7005	4625
HPRD ID		04411	01175
Ensembl ID		ENSG00000007866	ENSG00000092054
Uniprot IDs		Q99594	P12883
PDB IDs			1IK2 2FXM 2FXO 3DTP 4DB1
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Regulation Of Cell Proliferation Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Hippo Signaling Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Proliferation Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Tissue Development Organ Morphogenesis Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Lens Fiber Cell Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Epithelial Cell Differentiation Notch Signaling Pathway Positive Regulation Of Retinoic Acid Receptor Signaling Pathway	Positive Regulation Of Stem Cell Maintenance Regulation Of Stem Cell Maintenance Hippo Signaling Positive Regulation Of Stem Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Positive Regulation Of Cell Development Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Female Pregnancy Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Signal Transduction Lateral Mesoderm Development Transcription, DNA-templated Notochord Development RNA Biosynthetic Process Trophectodermal Cell Differentiation Paraxial Mesoderm Development Positive Regulation Of Cellular Metabolic Process Blastocyst Formation RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Embryonic Heart Tube Morphogenesis Cellular Macromolecule Biosynthetic Process Embryo Implantation Embryo Development Macromolecule Biosynthetic Process Embryonic Heart Tube Development Cell Fate Specification Blastocyst Development Reproductive Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Mesoderm Development Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process
Tagcloud ?			5188delaga aggregates alert autosomal biopsies cd3 cd68 cd8 comprising contained distal endomysial inclusion k1729del laing member mhc myopathy myositis p62 pathologic perivascular physicians possibility rimmed smi specimen typical vacuoles
Tagcloud (Difference) ?			5188delaga aggregates alert autosomal biopsies cd3 cd68 cd8 comprising contained distal endomysial inclusion k1729del laing member mhc myopathy myositis p62 pathologic perivascular physicians possibility rimmed smi specimen typical vacuoles
Tagcloud (Intersection) ?