TEAD3 and E2F3

Number of citations of the paper that reports this interaction (PMID 12748276)
36

Data Source:
BioGRID (two hybrid)

		TEAD3	E2F3
Gene Name		TEA domain family member 3	E2F transcription factor 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor Complex	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Golgi Apparatus Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding	Core Promoter Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Gene Expression Hippo Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Stem Cell Maintenance	Mitotic Cell Cycle Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Positive Regulation Of Cell Proliferation Positive Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	Signaling by NOTCH DNA Replication Pre-Initiation G1 Phase Cellular Senescence M/G1 Transition Regulation of DNA replication CDC6 association with the ORC:origin complex Oncogene Induced Senescence Cell Cycle, Mitotic Assembly of the pre-replicative complex Cyclin D associated events in G1 Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence G2 Phase Pre-NOTCH Expression and Processing Association of licensing factors with the pre-replicative complex Mitotic G2-G2/M phases Mitotic G1-G1/S phases
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		13 interactors: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 WWTR1 YAP1	23 interactors: ATAD2 CCNA2 CDK3 CREBBP FHL2 FZR1 HCFC1 HELLS MGA MYBL2 PKIB RB1 RNF144A RYBP SP1 SPIB SRA1 TEAD3 TFDP1 TFDP2 TFE3 WNK1 YY1
Entrez ID		7005	1871
HPRD ID		04411	02693
Ensembl ID		ENSG00000007866	ENSG00000112242
Uniprot IDs		Q99594	O00716 Q24JQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Regulation Of Cell Proliferation Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Hippo Signaling Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Proliferation Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Tissue Development Organ Morphogenesis Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Lens Fiber Cell Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Epithelial Cell Differentiation Notch Signaling Pathway Positive Regulation Of Retinoic Acid Receptor Signaling Pathway	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Positive Regulation Of Metabolic Process Mitotic Nuclear Division Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Cell Cycle DNA-templated Transcription, Initiation Mitotic Cell Cycle Process Regulation Of Cellular Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Cellular Metabolic Process Cell Cycle Process Cell Division Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Enucleate Erythrocyte Differentiation Negative Regulation Of Gene Expression Negative Regulation Of Transferase Activity Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle
Tagcloud ?			34a arrest carcinogenic chemokine concern concerned creates ct cytotoxicity doses frequent greatly involves ionizing killer mammographies medical micro mir mirna overexposure pathways patterns presentation radiation ray scans successfully workers
Tagcloud (Difference) ?			34a arrest carcinogenic chemokine concern concerned creates ct cytotoxicity doses frequent greatly involves ionizing killer mammographies medical micro mir mirna overexposure pathways patterns presentation radiation ray scans successfully workers
Tagcloud (Intersection) ?