PRDX2 and EXOC6

Number of citations of the paper that reports this interaction (PMID 21163940)
13

Data Source:
BioGRID (two hybrid)

		PRDX2	EXOC6
Gene Name		peroxiredoxin 2	exocyst complex component 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Exocyst Cytosol Plasma Membrane
	Molecular Function	Thioredoxin Peroxidase Activity Antioxidant Activity
	Biological Process	Response To Reactive Oxygen Species Response To Oxidative Stress Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Oxidation-reduction Process	Vesicle Docking Involved In Exocytosis Organelle Organization Protein Transport Erythrocyte Differentiation Cellular Protein Metabolic Process Membrane Organization
Pathways		Detoxification of Reactive Oxygen Species	Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs		3-Sulfinoalanine N-Carbamoyl-Alanine
Diseases
GWAS
Protein-Protein Interactions		23 interactors: A2M APOE APP BAD CA4 CD320 CDC37 COPS5 ECSIT EXOC6 IFIT5 MAST1 NLGN3 PDGFRB PPP2R1A PPP2R1B PRDX4 PSEN1 RNF32 SAT1 SUMO4 UTY YWHAZ	11 interactors: APP CYP2C8 ECSIT EXOSC1 GCDH LOXL4 MAST1 NOS3 PRDX2 PSEN2 RNF32
Entrez ID		7001	54536
HPRD ID		02763	10216
Ensembl ID		ENSG00000167815	ENSG00000138190
Uniprot IDs		A6NIW5 B4DF70 P32119	B3KXY5 E7EW84 F2Z2Q3 Q8TAG9
PDB IDs		1QMV
Enriched GO Terms of Interacting Partners?		Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Signal Transduction Regulation Of Signaling Establishment Of Localization In Cell Secretion By Cell Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Cell Death Secretion Intracellular Signal Transduction Cellular Localization Cellular Component Assembly Vesicle-mediated Transport Regulation Of Cellular Component Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Response To Oxidative Stress Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Synapse Assembly Protein Metabolic Process Positive Regulation Of Signal Transduction Membrane Organization Immune Response Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Regulation Of Catalytic Activity Homeostatic Process Anatomical Structure Morphogenesis Positive Regulation Of Apoptotic Process Regulation Of Receptor Activity Positive Regulation Of Programmed Cell Death Apoptotic Process Regulation Of MAPK Cascade Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Apoptotic Process Programmed Cell Death Developmental Process Cell Death Anion Transport Regulation Of Proteolysis Death Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Protein Phosphorylation Regulation Of Cell Death Mitochondrial Transport Postsynaptic Membrane Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Oxidation-reduction Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Epidermal Growth Factor-activated Receptor Activity Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Protein Tyrosine Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Catabolic Process Regulation Of Oxidoreductase Activity Axon Guidance Regulation Of ERBB Signaling Pathway Smooth Muscle Hyperplasia Synaptic Growth At Neuromuscular Junction Reactive Oxygen Species Metabolic Process Regulation Of Receptor Activity Cellular Amino Acid Catabolic Process Axonogenesis Locomotion Collateral Sprouting In Absence Of Injury Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Notch Signaling Pathway Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Protein Binding Smooth Muscle Adaptation Chemotaxis Anatomical Structure Morphogenesis Negative Regulation Of Muscle Hyperplasia Collateral Sprouting Regulation Of Systemic Arterial Blood Pressure By Endothelin Axon Midline Choice Point Recognition Neuron Projection Morphogenesis Movement Of Cell Or Subcellular Component Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cell Morphogenesis Involved In Differentiation Regulation Of Extrinsic Apoptotic Signaling Pathway Carboxylic Acid Catabolic Process Regulation Of The Force Of Heart Contraction By Chemical Signal Regulation Of Peptidyl-tyrosine Phosphorylation Lysine Catabolic Process Arginine Catabolic Process Omega-hydroxylase P450 Pathway Negative Regulation Of Cellular Protein Metabolic Process Neuron Remodeling Neuron Projection Development Exit From Mitosis Metabolic Process Cell Projection Morphogenesis Lung Development
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Tagcloud (Difference) ?		2de angustifolia apoa1 atp5a1 atp5a1were bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically predictedinteractions scrutinized searching slowing snca string sum tof
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