PRDX2 and CD320

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		PRDX2	CD320
Gene Name		peroxiredoxin 2	CD320 molecule
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Vesicular Exosome	Endoplasmic Reticulum Plasma Membrane Endosome Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Thioredoxin Peroxidase Activity Antioxidant Activity	Growth Factor Activity Cobalamin Binding
	Biological Process	Response To Reactive Oxygen Species Response To Oxidative Stress Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Hydrogen Peroxide Catabolic Process Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Oxidation-reduction Process	Regulation Of Cell Growth Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Cobalamin Metabolic Process Regulation Of Vitamin Metabolic Process Small Molecule Metabolic Process
Pathways		Detoxification of Reactive Oxygen Species	Metabolism of vitamins and cofactors Defective GIF causes intrinsic factor deficiency Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Cobalamin (Cbl, vitamin B12) transport and metabolism Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs		3-Sulfinoalanine N-Carbamoyl-Alanine
Diseases
GWAS
Protein-Protein Interactions		23 interactors: A2M APOE APP BAD CA4 CD320 CDC37 COPS5 ECSIT EXOC6 IFIT5 MAST1 NLGN3 PDGFRB PPP2R1A PPP2R1B PRDX4 PSEN1 RNF32 SAT1 SUMO4 UTY YWHAZ	1 interactors: PRDX2
Entrez ID		7001	51293
HPRD ID		02763	05929
Ensembl ID		ENSG00000167815	ENSG00000167775
Uniprot IDs		A6NIW5 B4DF70 P32119	Q9NPF0
PDB IDs		1QMV
Enriched GO Terms of Interacting Partners?		Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Signal Transduction Regulation Of Signaling Establishment Of Localization In Cell Secretion By Cell Regulation Of Kinase Activity Regulation Of Phosphorylation Positive Regulation Of Cell Death Secretion Intracellular Signal Transduction Cellular Localization Cellular Component Assembly Vesicle-mediated Transport Regulation Of Cellular Component Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Response To Oxidative Stress Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Protein Kinase Activity Synapse Assembly Protein Metabolic Process Positive Regulation Of Signal Transduction Membrane Organization Immune Response Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Regulation Of Catalytic Activity Homeostatic Process Anatomical Structure Morphogenesis Positive Regulation Of Apoptotic Process Regulation Of Receptor Activity Positive Regulation Of Programmed Cell Death Apoptotic Process Regulation Of MAPK Cascade Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Apoptotic Process Programmed Cell Death Developmental Process Cell Death Anion Transport Regulation Of Proteolysis Death Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Protein Phosphorylation Regulation Of Cell Death Mitochondrial Transport Postsynaptic Membrane Organization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Hydrogen Peroxide Catabolic Process Removal Of Superoxide Radicals Cellular Response To Superoxide Response To Superoxide Response To Oxygen Radical Hydrogen Peroxide Metabolic Process Superoxide Metabolic Process Cellular Response To Reactive Oxygen Species Reactive Oxygen Species Metabolic Process Negative Regulation Of Neuron Apoptotic Process Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Negative Regulation Of Neuron Death Regulation Of Neuron Apoptotic Process Regulation Of Neuron Death Response To Oxidative Stress Response To Inorganic Substance
Tagcloud ?		2de angustifolia apoa1 atp5a1 atp5a1were bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically predictedinteractions scrutinized searching slowing snca string sum tof	aberrations ann arbor barr bcl2 cd10 cd45 cd56 clinicopathologic cutaneous dnmt3b ebv epstein extranodal hodgkin ic immunocompetent immunodeficiency immunologic pbl pbls plasmablastic positivity pt ptp4a3 recipients summarized testis unpublished
Tagcloud (Difference) ?		2de angustifolia apoa1 atp5a1 atp5a1were bioinformatics caliber david diminishing dysregulated histopathology hspa5 kegg la lavandula lavender le likewise ontology operate pharmaceutically predictedinteractions scrutinized searching slowing snca string sum tof	aberrations ann arbor barr bcl2 cd10 cd45 cd56 clinicopathologic cutaneous dnmt3b ebv epstein extranodal hodgkin ic immunocompetent immunodeficiency immunologic pbl pbls plasmablastic positivity pt ptp4a3 recipients summarized testis unpublished
Tagcloud (Intersection) ?