SULT1E1 and EEF1A1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SULT1E1	EEF1A1
Gene Name		sulfotransferase family 1E, estrogen-preferring, member 1	eukaryotic translation elongation factor 1 alpha 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol	Extracellular Space Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Estrone Sulfotransferase Activity Steroid Binding Flavonol 3-sulfotransferase Activity Steroid Sulfotransferase Activity	Translation Elongation Factor Activity GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Poly(A) RNA Binding
	Biological Process	Xenobiotic Metabolic Process Female Pregnancy Steroid Metabolic Process Estrogen Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process Cellular Response To Epidermal Growth Factor Stimulus
Pathways		Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Cytosolic sulfonation of small molecules Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)	HSF1 activation Translation Cellular response to heat stress Peptide chain elongation Eukaryotic Translation Elongation
Drugs		Cyclizine Adenosine-3\'-5\'-Diphosphate 3\'-Phosphate-Adenosine-5\'-Phosphate Sulfate 3,5,3\',5\'-Tetrachloro-Biphenyl-4,4\'-Diol
Diseases
GWAS
Protein-Protein Interactions		13 interactors: BMPR2 C14orf1 COPS6 EEF1A1 ENOX1 IGSF21 LRIF1 PDE9A RBM48 SETDB1 SULT2B1 TP53 UNC119	123 interactors: ABTB2 ACTB ALPL ANKRD24 ANXA7 APLP1 ARIH2 AXIN1 BBS1 BBS2 BBS4 BRMS1 BTBD2 CASP2 CCDC130 CCL18 CDC25A CDKN1A CKS2 COX17 CRADD CRCT1 CSRP2 DARS DIABLO DLEU1 DUSP7 DYNLL1 EIF3F EXOSC4 FAS GADD45A GADD45G GSK3B HSPE1 HTRA2 IKBKG IMMT ITGB1BP1 ITSN1 KCNE3 KIF1B KRAS LAMA4 LAMTOR1 LAMTOR5 LSM3 MAD2L1BP MAGED2 MAP3K14 MAPK14 MLLT3 MNAT1 MRM1 MRPL42 MTRNR2L1 MYOC NEU1 NRAS NREP ORMDL3 PABPC4 PAEP PAFAH1B3 PAPSS1 PCDHA4 PFN2 PHYHIP PKN2 PLAUR PLCG1 POLE2 POLR2C PQBP1 PRKCD PSG9 PSMD11 PTPN4 PTPRCAP RAB27A RAP2A RBBP8 RFC5 RGS12 RNF10 RPA2 RPLP1 RRAS RSRC1 SARS2 SDHAF2 SERPINB9 SFN SHBG SMAD2 SMAD4 SMN1 SNCA SPP1 SSR1 STAT6 STMN2 SULT1E1 TAF9 TGIF1 TK1 TMPRSS3 TNFSF11 TP53BP2 TPT1 TRDMT1 TSPY1 TSPYL2 TTR UBQLN4 WARS XPO5 XRN2 YWHAG ZBTB16 ZCCHC10 ZNF24 ZPR1
Entrez ID		6783	1915
HPRD ID		08966	00559
Ensembl ID		ENSG00000109193	ENSG00000156508
Uniprot IDs		P49888 Q53X91	P68104 Q6IPS9
PDB IDs		1G3M 1HY3 4JVL 4JVM 4JVN	1SYW
Enriched GO Terms of Interacting Partners?			Apoptotic Process Programmed Cell Death Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Cell Death Death Regulation Of Phosphorylation Developmental Process Regulation Of Phosphorus Metabolic Process Response To Stimulus Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Kinase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Cell Differentiation Anatomical Structure Development Regulation Of Catalytic Activity Regulation Of Signal Transduction Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Cell Death Multicellular Organismal Development Regulation Of Apoptotic Process Cellular Response To Stimulus Response To Stress Cellular Response To Growth Factor Stimulus Response To External Stimulus Positive Regulation Of Protein Modification Process Regulation Of Signaling Cellular Response To Stress Positive Regulation Of Programmed Cell Death Response To Growth Factor Positive Regulation Of Catalytic Activity System Development Positive Regulation Of Phosphorylation Positive Regulation Of Cell Death Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Nervous System Development Positive Regulation Of Protein Kinase Activity Positive Regulation Of Transferase Activity Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process Positive Regulation Of Kinase Activity
Tagcloud ?		analyzing bovine caruncular catalyzed conflict conflicting esr esrs estrogens expresses giant placentas pools posttranscriptional produces resolve sorting sulfonation tgc tgcs transcript trophoblast unable uninucleated utc utcs virtually	akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		analyzing bovine caruncular catalyzed conflict conflicting esr esrs estrogens expresses giant placentas pools posttranscriptional produces resolve sorting sulfonation tgc tgcs transcript trophoblast unable uninucleated utc utcs virtually	akap6 atf7 atxn1 bmpr2 categorize deltan grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?