SSRP1 and SREK1

Number of citations of the paper that reports this interaction (PMID 14559993)
9

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SSRP1	SREK1
Gene Name		structure specific recognition protein 1	splicing regulatory glutamine/lysine-rich protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Nucleolus Cytoplasm	Nucleoplasm Spliceosomal Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	DNA Replication DNA Repair Chromatin Remodeling Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Viral Transcription	MRNA Processing RNA Splicing
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: CHD1 CHMP1B CSNK2A1 DHX9 EXOSC10 H2AFX H3F3A HIST1H3A HIST1H4A HIST2H2AC HIST2H2BE MCM4 MYCBP NEK9 RAN ROBO2 SPI1 SREK1 SRF SUMO1	55 interactors: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GNB2L1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2
Entrez ID		6749	140890
HPRD ID		05061	18043
Ensembl ID		ENSG00000149136	ENSG00000153914
Uniprot IDs		Q08945	E5RFV3 Q8WXA9
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Conformation Change Chromosome Organization Organelle Organization Nucleosome Assembly Chromatin Assembly Nucleobase-containing Compound Metabolic Process Nucleosome Organization DNA Methylation On Cytosine Chromatin Assembly Or Disassembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein-DNA Complex Assembly Chromatin Silencing At RDNA Cellular Nitrogen Compound Metabolic Process DNA Packaging Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Organization Nitrogen Compound Metabolic Process Chromatin Silencing Gene Expression DNA Metabolic Process DNA Methylation Mitotic Cell Cycle DNA Replication-dependent Nucleosome Assembly DNA Duplex Unwinding DNA Geometric Change DNA Modification Cell Cycle Gene Silencing Regulation Of Gene Expression Positive Regulation Of Cell Growth Nucleus Organization Cellular Macromolecular Complex Assembly Cell Cycle Process Mitotic Cell Cycle Process Apoptotic Process Involved In Development DNA Replication-independent Nucleosome Assembly Olfactory Bulb Development Regulation Of Cellular Component Organization Olfactory Lobe Development Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Patterning Of Blood Vessels Positive Regulation Of Growth Contractile Actin Filament Bundle Assembly Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process	RNA Splicing RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Export From Nucleus Termination Of RNA Polymerase II Transcription RNA Transport MRNA Export From Nucleus RNA Localization MRNA 3'-end Processing Nuclear Export MRNA Transport Cellular Metabolic Process RNA 3'-end Processing DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Regulation Of MRNA Stability Regulation Of RNA Stability Nucleocytoplasmic Transport Nuclear Transport Spliceosomal Complex Assembly Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing MRNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cytoplasmic Transport Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		coordinates cryptic displacement facilitates fact h2b h3k36me3 hypb intragenic kmt3a lys36 mammals methyltransferase modulates nucleosome nucleosomes observe occupancy positioned prevents recruitment repressing set2 setd2 spt16 spurious templates termed trimethylated
Tagcloud (Difference) ?		coordinates cryptic displacement facilitates fact h2b h3k36me3 hypb intragenic kmt3a lys36 mammals methyltransferase modulates nucleosome nucleosomes observe occupancy positioned prevents recruitment repressing set2 setd2 spt16 spurious templates termed trimethylated
Tagcloud (Intersection) ?