SRY and SLC9A3R2

Number of citations of the paper that reports this interaction (PMID 9054412)
25

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SRY	SLC9A3R2
Gene Name		sex determining region Y	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck	Nucleus Cytoplasm Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Calmodulin Binding Transcription Factor Binding	Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Sex Differentiation Cell Differentiation Male Sex Determination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Male Gonad Development	Protein Complex Assembly Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: AR EP300 HDAC3 KPNB1 SLC9A3R2 SMAD3 ZNF208	35 interactors: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDPK1 PDZK1 PIK3CA PLCB3 PODXL PRKACA PTEN PTH1R RDX SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		6736	9351
HPRD ID		08364	05946
Ensembl ID			ENSG00000065054
Uniprot IDs		A7WPU8 Q05066	Q15599
PDB IDs		1HRY 1HRZ 1J46 1J47 2GZK	2D11 2HE4 2OCS
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Stability Positive Regulation Of Transcription Factor Import Into Nucleus Cellular Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Negative Regulation Of Signal Transduction Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Signaling Posttranscriptional Regulation Of Gene Expression Somitogenesis Response To Organic Substance Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription Factor Import Into Nucleus Histone H2B Acetylation Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Nucleobase-containing Compound Metabolic Process Protein Stabilization Negative Regulation Of Biosynthetic Process Somite Development Positive Regulation Of Protein Import Into Nucleus Regulation Of Signal Transduction Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Segmentation Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Signaling Notch Signaling Pathway Regulation Of Establishment Of Protein Localization RNA Metabolic Process Positive Regulation Of Integrin Biosynthetic Process Evasion Or Tolerance Of Host Defenses By Virus N-terminal Peptidyl-lysine Acetylation Nitrogen Compound Metabolic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Regulation Of Protein Import Into Nucleus Gene Expression Circadian Rhythm Negative Regulation Of Transcription From RNA Polymerase II Promoter Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly	Regulation Of Protein Kinase Activity Ion Homeostasis Transmembrane Transport Regulation Of Kinase Activity Regulation Of Ion Transport Positive Regulation Of Ion Transport Regulation Of Protein Phosphorylation Homeostatic Process Positive Regulation Of Transport Ion Transport Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorylation Ion Transmembrane Transport Cellular Cation Homeostasis Organic Anion Transport Cellular Ion Homeostasis Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Positive Regulation Of Protein Kinase Activity Blood Circulation Positive Regulation Of Cellular Protein Metabolic Process Anion Transport Platelet Activation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Transport Positive Regulation Of Protein Phosphorylation Sodium-independent Organic Anion Transport Carnitine Transport Cellular Chemical Homeostasis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Body Fluid Levels Monocarboxylic Acid Transport Sperm Capacitation Anion Transmembrane Transport Regulation Of Cellular Component Organization Sodium Ion Transport Inorganic Anion Transport Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Ion Transmembrane Transport Blood Coagulation Hemostasis Activation Of Protein Kinase Activity Positive Regulation Of Phosphorylation Quaternary Ammonium Group Transport Positive Regulation Of Cytosolic Calcium Ion Concentration
Tagcloud ?		aspartic assumed bearing built called calpains certain cleavable constitute demonstrates devoid erba extremely fos gata1 gata3 glutamic initiated motifs mutagenesis myo pest proline proteases rapid reportedly specifying strengthened threonine
Tagcloud (Difference) ?		aspartic assumed bearing built called calpains certain cleavable constitute demonstrates devoid erba extremely fos gata1 gata3 glutamic initiated motifs mutagenesis myo pest proline proteases rapid reportedly specifying strengthened threonine
Tagcloud (Intersection) ?