BMX and RUFY1

Number of citations of the paper that reports this interaction (PMID 11877430)
14

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, enzymatic study)
HPRD (two hybrid, in vivo)

		BMX	RUFY1
Gene Name		BMX non-receptor tyrosine kinase	RUN and FYVE domain containing 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Ruffle Membrane	Nucleus Cytoplasm Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signal Transducer Activity Receptor Binding Protein Binding ATP Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Lipid Binding Protein Transporter Activity
	Biological Process	Adaptive Immune Response Protein Phosphorylation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Mesoderm Development Cell Differentiation Intracellular Signal Transduction Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Innate Immune Response Protein Autophosphorylation T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway	Endocytosis Protein Transport Regulation Of Endocytosis
Pathways		Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS			Eating disorders ( 22911880)
Protein-Protein Interactions		23 interactors: APP BCAR1 BTK C12orf45 CASP3 CAV1 EGFR ERBB2 FBXO25 ITK KDR PAK1 PTK2 PTPN21 RAP1A RUFY1 RUFY2 SRC STAT1 STAT3 STAT5A TEC TNFRSF1B	17 interactors: AP3B2 AP3D1 AP3M1 AP3S1 BMX DIEXF EPHA3 GIT2 ITSN2 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TCF3 TXNDC17
Entrez ID		660	80230
HPRD ID		02111	15282
Ensembl ID		ENSG00000102010	ENSG00000176783
Uniprot IDs		P51813	A8K7B1 Q96T51
PDB IDs		2EKX 2YS2 3SXR 3SXS	2YQM 2YW8
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Immune System Process Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Intracellular Signal Transduction Response To Organic Substance Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Organic Substance Response To Growth Factor Regulation Of Immune Response Fc Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Cellular Response To Organonitrogen Compound Positive Regulation Of Cellular Metabolic Process Immune Response-regulating Signaling Pathway Response To Wounding Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Differentiation Positive Regulation Of Metabolic Process Response To Stress Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Response To Organonitrogen Compound Cellular Response To Hormone Stimulus Neurotrophin Signaling Pathway Wound Healing Regulation Of Cell Death Signal Transduction Peptidyl-amino Acid Modification Response To Hormone Response To Peptide Hormone Immune Response Protein Phosphorylation Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cell Activation Signaling Response To Peptide Cell Communication Growth Hormone Receptor Signaling Pathway Regulation Of Protein Kinase Activity	Anterograde Synaptic Vesicle Transport Intracellular Protein Transport Anterograde Axon Cargo Transport Synaptic Vesicle Transport Axon Cargo Transport Rab Protein Signal Transduction Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Establishment Of Vesicle Localization Intracellular Transport Vesicle Localization Protein Localization Microtubule-based Transport Establishment Of Organelle Localization Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Signaling Cell Communication Organelle Localization Cellular Localization Ras Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Synaptic Transmission Microtubule-based Movement Cytoplasmic Transport Cell-cell Signaling Endosomal Transport Regulation Of Ras GTPase Activity Transport Phagolysosome Assembly Involved In Apoptotic Cell Clearance Small GTPase Mediated Signal Transduction Golgi Vesicle Transport Regulation Of Ras Protein Signal Transduction Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Synaptic Vesicle Membrane Organization Cellular Response To Stimulus Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Regulation Of GTPase Activity Canonical Wnt Signaling Pathway Receptor Internalization Involved In Canonical Wnt Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Endosome Size Response To Stimulus Membrane Organization Eye Pigment Biosynthetic Process Movement Of Cell Or Subcellular Component
Tagcloud ?		additive androgen attenuation btk chemo confer correlates ctn06 docetaxel dtx dual etk grades healing herein immortalized impeded independence killing never pc3 perception prostate raf sensitizer tec vegfr wound xenograft
Tagcloud (Difference) ?		additive androgen attenuation btk chemo confer correlates ctn06 docetaxel dtx dual etk grades healing herein immortalized impeded independence killing never pc3 perception prostate raf sensitizer tec vegfr wound xenograft
Tagcloud (Intersection) ?