BMX and RUFY2

Number of citations of the paper that reports this interaction (PMID 11877430)
14

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		BMX	RUFY2
Gene Name		BMX non-receptor tyrosine kinase	RUN and FYVE domain containing 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Ruffle Membrane	Nucleus
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signal Transducer Activity Receptor Binding Protein Binding ATP Binding Metal Ion Binding	Metal Ion Binding
	Biological Process	Adaptive Immune Response Protein Phosphorylation Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cell Adhesion Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Mesoderm Development Cell Differentiation Intracellular Signal Transduction Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Innate Immune Response Protein Autophosphorylation T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway
Pathways		Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: APP BCAR1 BTK C12orf45 CASP3 CAV1 EGFR ERBB2 FBXO25 ITK KDR PAK1 PTK2 PTPN21 RAP1A RUFY1 RUFY2 SRC STAT1 STAT3 STAT5A TEC TNFRSF1B	4 interactors: BMX DUSP23 EPHA3 SF3B3
Entrez ID		660	55680
HPRD ID		02111	11526
Ensembl ID		ENSG00000102010	ENSG00000204130
Uniprot IDs		P51813	B4DFR0 Q8WXA3
PDB IDs		2EKX 2YS2 3SXR 3SXS
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Immune System Process Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Regulation Of Cell Proliferation Intracellular Signal Transduction Response To Organic Substance Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Cellular Response To Organic Substance Response To Growth Factor Regulation Of Immune Response Fc Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Cellular Response To Organonitrogen Compound Positive Regulation Of Cellular Metabolic Process Immune Response-regulating Signaling Pathway Response To Wounding Defense Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Differentiation Positive Regulation Of Metabolic Process Response To Stress Phosphorylation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Response To Organonitrogen Compound Cellular Response To Hormone Stimulus Neurotrophin Signaling Pathway Wound Healing Regulation Of Cell Death Signal Transduction Peptidyl-amino Acid Modification Response To Hormone Response To Peptide Hormone Immune Response Protein Phosphorylation Cell Activation Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cell Activation Signaling Response To Peptide Cell Communication Growth Hormone Receptor Signaling Pathway Regulation Of Protein Kinase Activity	Peptidyl-tyrosine Phosphorylation Fasciculation Of Motor Neuron Axon Fasciculation Of Sensory Neuron Axon
Tagcloud ?		additive androgen attenuation btk chemo confer correlates ctn06 docetaxel dtx dual etk grades healing herein immortalized impeded independence killing never pc3 perception prostate raf sensitizer tec vegfr wound xenograft	bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite never outgrowth pc12 plekhm2 rab rab1 rab1a rab33 rab35 rab41 rab6a rabs rbd35 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Difference) ?		additive androgen attenuation btk chemo confer correlates ctn06 docetaxel dtx dual etk grades healing herein immortalized impeded independence killing pc3 perception prostate raf sensitizer tec vegfr wound xenograft	bait consists dennd5a domains fluorescently gtp gtpases minimal named neurite outgrowth pc12 plekhm2 rab rab1 rab1a rab33 rab35 rab41 rab6a rabs rbd35 run rusc2 succeeded tagged trafficking trapper
Tagcloud (Intersection) ?		never