TRA2B and SRSF10

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		TRA2B	SRSF10
Gene Name		transformer 2 beta homolog (Drosophila)	serine/arginine-rich splicing factor 10
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	Nucleotide Binding MRNA Binding Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding RS Domain Binding Unfolded Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated MRNA Splice Site Selection MRNA Export From Nucleus Cytoplasmic Transport Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Menarche (age at onset) ( 21102462)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		26 interactors: CDK6 HINFP HIPK3 HNRNPA1 IVNS1ABP LUM NGFR NXF1 RBMX RBMXL2 RBMY1A1 RNPS1 SREK1 SRPK1 SRPK2 SRSF10 SRSF2 SRSF3 SRSF4 SRSF6 SRSF9 TNPO3 YTHDC1 YWHAG YWHAZ ZRANB2	10 interactors: CSNK2A1 FUS SNRNP70 SREK1 SRSF1 SRSF4 TRA2A TRA2B YWHAB YWHAG
Entrez ID		6434	10772
HPRD ID		04097	05562
Ensembl ID			ENSG00000188529
Uniprot IDs		P62995	O75494
PDB IDs		2CQC 2KXN 2RRA 2RRB
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing RNA Processing MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome RNA Export From Nucleus Regulation Of MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing MRNA Export From Nucleus MRNA Transport Nuclear Export RNA Transport Negative Regulation Of MRNA Splicing, Via Spliceosome RNA Localization Negative Regulation Of RNA Splicing Nucleocytoplasmic Transport Nuclear Transport Gene Expression Termination Of RNA Polymerase II Transcription Cytoplasmic Transport RNA Metabolic Process DNA-templated Transcription, Termination MRNA 3'-end Processing Intracellular Transport RNA 3'-end Processing Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Establishment Of Localization In Cell Regulation Of Alternative MRNA Splicing, Via Spliceosome Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Splice Site Selection Cellular Localization Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Ribonucleoprotein Complex Biogenesis Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Metabolic Process Metabolic Process	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Gene Expression RNA Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Positive Regulation Of Mitochondrion Organization MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Regulation Of Mitochondrion Organization RNA 3'-end Processing Nuclear Export MRNA Transport RNA Transport RNA Localization MRNA 5'-splice Site Recognition Negative Regulation Of Protein Dephosphorylation Intracellular Transport Intrinsic Apoptotic Signaling Pathway Cellular Metabolic Process Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Insulin Stimulus Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Intracellular Transport Regulation Of RNA Metabolic Process Negative Regulation Of Protein Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Organelle Organization Response To Insulin Regulation Of Cellular Protein Metabolic Process Apoptotic Process
Tagcloud ?		3r 4r annonacin attractive brains characterised depending excess exists exon far intervene isoforms link microtubule mitochondrial neurodegenerative others palsy predominant prototypical psp repeat splicing srsf2 supranuclear tau upstream whilst	antigens autoregulatory b10 correlates deaf1 deformed drive hek293t hyperglycemia inflammation isoform lnscs lymph mediate nod nodes plns pta ptas ptbp2 s961 scid splenocytes spliced splicing stromal t1d tolerance var1
Tagcloud (Difference) ?		3r 4r annonacin attractive brains characterised depending excess exists exon far intervene isoforms link microtubule mitochondrial neurodegenerative others palsy predominant prototypical psp repeat srsf2 supranuclear tau upstream whilst	antigens autoregulatory b10 correlates deaf1 deformed drive hek293t hyperglycemia inflammation isoform lnscs lymph mediate nod nodes plns pta ptas ptbp2 s961 scid splenocytes spliced stromal t1d tolerance var1
Tagcloud (Intersection) ?		splicing