SCNN1B and SCNN1D

Number of citations of the paper that reports this interaction (PMID 7499195)
42

Data Source:
HPRD (in vivo)

		SCNN1B	SCNN1D
Gene Name		sodium channel, non voltage gated 1 beta subunit	sodium channel, non voltage gated 1 delta subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Apical Plasma Membrane Sodium Channel Complex Extracellular Vesicular Exosome	Plasma Membrane Actin Cytoskeleton Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Ligand-gated Sodium Channel Activity WW Domain Binding	Protein Binding Ligand-gated Sodium Channel Activity
	Biological Process	Sodium Ion Transport Excretion Ion Transmembrane Transport Sodium Ion Transmembrane Transport Multicellular Organismal Water Homeostasis Response To Stimulus Sensory Perception Of Taste Sodium Ion Homeostasis Transmembrane Transport	Sodium Ion Transport Ion Transmembrane Transport Sodium Ion Transmembrane Transport Response To Stimulus Sensory Perception Of Taste Transmembrane Transport
Pathways		Ion channel transport Stimuli-sensing channels	Ion channel transport Stimuli-sensing channels
Drugs		Triamterene Amiloride	Triamterene Amiloride
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ANK3 CNTN1 EPN1 HECW1 ITCH NEDD4 NEDD4L NFASC SCNN1A SCNN1D SCNN1G STX1A WWP2	2 interactors: SCNN1B SCNN1G
Entrez ID		6338	6339
HPRD ID		02861	03209
Ensembl ID		ENSG00000168447	ENSG00000162572
Uniprot IDs		B2R812 P51168	A6NNF7 P51172
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Regulation Of Membrane Potential Sodium Ion Homeostasis Protein K63-linked Ubiquitination Positive Regulation Of Sodium Ion Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Transporter Activity Protein Polyubiquitination Excretion Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Water Homeostasis Sensory Perception Of Taste Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Sodium Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Ion Transport Negative Regulation Of Sodium Ion Transport Negative Regulation Of Ion Transport Negative Regulation Of Potassium Ion Transmembrane Transport Interaction With Host Locomotion Positive Regulation Of Transport Negative Regulation Of Transport Notch Signaling Pathway Negative Regulation Of Potassium Ion Transport Cellular Macromolecule Catabolic Process Regulation Of Ion Transmembrane Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Synapse Organization Metal Ion Homeostasis Regulation Of Sodium Ion Transmembrane Transporter Activity Viral Life Cycle Positive Regulation Of Ion Transport Sodium Ion Transmembrane Transport Viral Process Regulation Of Membrane Depolarization Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Signal Transduction Ion Homeostasis Protein K48-linked Ubiquitination	Sodium Ion Homeostasis Excretion Multicellular Organismal Water Homeostasis Water Homeostasis Sensory Perception Of Taste Sodium Ion Transmembrane Transport Sodium Ion Transport Sensory Perception Of Chemical Stimulus Metal Ion Homeostasis Ion Homeostasis Regulation Of Body Fluid Levels Monovalent Inorganic Cation Transport Sensory Perception Metal Ion Transport Chemical Homeostasis Cation Transmembrane Transport Neurological System Process Cation Transport Ion Transmembrane Transport Homeostatic Process Transmembrane Transport Ion Transport Transport
Tagcloud ?		aldosterone atp1a1 atpasealpha1 betamethasone breaths compliance corticosteroid corticosteroids elastin enac enacalpha enacbeta epithelia fetuses gestation gr inflation infused infusions intravenously mineralocorticoid mr ovine pressures reabsorption stepwise synergy transcriptomic
Tagcloud (Difference) ?		aldosterone atp1a1 atpasealpha1 betamethasone breaths compliance corticosteroid corticosteroids elastin enac enacalpha enacbeta epithelia fetuses gestation gr inflation infused infusions intravenously mineralocorticoid mr ovine pressures reabsorption stepwise synergy transcriptomic
Tagcloud (Intersection) ?