RPS15A and DDX39B

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		RPS15A	DDX39B
Gene Name		ribosomal protein S15a	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome	Transcription Export Complex Nucleus Nucleoplasm Spliceosomal Complex U4 SnRNP U6 SnRNP Cytoplasm Nuclear Speck
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Poly(A) RNA Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity U6 SnRNA Binding U4 SnRNA Binding ATP-dependent Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Cell Proliferation Response To Virus Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Positive Regulation Of Cell Cycle	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Export From Nucleus RNA Splicing RNA Secondary Structure Unwinding Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of DNA Damage Checkpoint
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CALM1 CDC37 DDX39B ELF5 EWSR1 VHL	24 interactors: ALYREF BARD1 DDX39A DNM2 EXOSC9 FANCA HIPK2 HNRNPLL IL7R NCBP2 PIAS2 RBM39 RPS15A SARNP SREK1 STRN4 TDG THOC3 THOC5 THOC6 THOC7 TUBB3 YWHAG ZHX1
Entrez ID		6210	7919
HPRD ID		04723	00805
Ensembl ID		ENSG00000134419	ENSG00000198563
Uniprot IDs		B2R4W8 P62244	Q13838
PDB IDs		3J3A	1T5I 1T6N 1XTI 1XTJ 1XTK
Enriched GO Terms of Interacting Partners?		Protein Stabilization Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Stability RNA Secondary Structure Unwinding Negative Regulation Of DNA Damage Checkpoint Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Metabolic Process Regulation Of Cell Cycle Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Cellular Metabolic Process Viral MRNA Export From Host Cell Nucleus Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of DNA Damage Checkpoint Detection Of Calcium Ion Positive Regulation Of Transcription, DNA-templated Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Gene Expression Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Metabolic Process Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Posttranscriptional Regulation Of Gene Expression Regulation Of Interferon-gamma-mediated Signaling Pathway Polysaccharide Catabolic Process Regulation Of Response To Interferon-gamma Positive Regulation Of Monooxygenase Activity Mammary Gland Epithelial Cell Differentiation Regulation Of Cell Cycle Process Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Cellular Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Ectoderm Development Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity	MRNA Export From Nucleus RNA Export From Nucleus Viral MRNA Export From Host Cell Nucleus MRNA Metabolic Process Nuclear Export MRNA Transport RNA Transport RNA Localization MRNA Processing RNA Splicing Intracellular Transport Of Virus RNA Processing Nucleocytoplasmic Transport Nuclear Transport RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cytoplasmic Transport Viral Life Cycle Viral Process Intracellular Transport Establishment Of Localization In Cell Cellular Metabolic Process Cellular Localization Regulation Of RNA Export From Nucleus Positive Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription, Elongation Nuclear-transcribed MRNA Catabolic Process Regulation Of RNA Metabolic Process MRNA Catabolic Process Termination Of RNA Polymerase II Transcription RNA Catabolic Process Regulation Of Intracellular Transport Aromatic Compound Catabolic Process Regulation Of Nucleocytoplasmic Transport Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Transport Regulation Of DNA-templated Transcription, Elongation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Metabolic Process SnRNA Export From Nucleus
Tagcloud ?		4e 4f accounts brassica cdc33 cdc33ts4 cerevisiae clone drosophila eif grow multicopy name napus oogenesis phenomenon produces rescuing ribosomal saccharomyces shuttle stabilization suppressing temperature termed unaffected unrelated yeast	22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax
Tagcloud (Difference) ?		4e 4f accounts brassica cdc33 cdc33ts4 cerevisiae clone drosophila eif grow multicopy name napus oogenesis phenomenon produces rescuing ribosomal saccharomyces shuttle stabilization suppressing temperature termed unaffected unrelated yeast	22c 348c acc agc agt amazon asymptomatic bat1 brazilian categorized cc complicated ga gg ggt haplotypes helicase il6 malaria mild ncoi nlaiii plasmodium polymorphisms postulation restriction snps uninfected vivax
Tagcloud (Intersection) ?